Results 1 to 10 of about 38,529 (119)
Co-occurrence of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder and hepatocellular carcinoma: A case report [PDF]
Journal of International Medical ResearchNeuromyelitis optica spectrum disorder is a rare, relapsing autoimmune disease in which the immune system attacks the central nervous system, primarily the optic nerves and spinal cord.
Cheng Li, Weijing Liao, Di Long
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Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4 [PDF]
European Cells & Materials, 2021 The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis ...
JW Snuggs, RAD Bunning, CL Le Maitre
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Frontiers in Physiology, 2021 Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho +4 more
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Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors. [PDF]
PLoS ONE, 2015 We analyzed aquaporin 4 and -1 expression in subependymomas, benign and slow growing brain tumors WHO grade I. Ten subependymoma cases were investigated, five of the fossa inferior and five of the fossa superior.Using immunohistochemistry, we observed ...
Susan Noell +5 more
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Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes
Acta Neuropathologica Communications, 2020 Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the ...
Irina Tsymala +23 more
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European Radiology Experimental, 2021 Background Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an effective treatment for reducing ...
Takuya Urushihata +9 more
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Brain aquaporin-4 expression in the rat septic model (immunohistochemical study)
Medičnì Perspektivi, 2022 The study aimed to determine aquaporin-4 expression in different brain regions was performed in Wistar rats subjected to cecal ligation and puncture (CLP) septic model.
T.V. Shulyatnikova, V.O. Tumanskiy
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Aquaporin-4 Expression in Meningioma Malignancy Progression
Brazilian Neurosurgery, 2023 Objectives The aim of the present study is to analyze if aquaporin-4 (AQP4) may also be a tumor progression marker for meningiomas. Methods This is an immunohistochemistry study realized at the Universidade de São Paulo, São Paulo, state of ...
Benedito Jamilson Araújo Pereira +5 more
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Neuromyelitis optica pathogenesis and aquaporin 4
Journal of Neuroinflammation, 2008 Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly features immunopathology in the optic nerves and the spinal cord.
Kerr Douglas +3 more
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The Role of Aquaporins in Spinal Cord Injury
Cells, 2023 Edema formation following traumatic spinal cord injury (SCI) exacerbates secondary injury, and the severity of edema correlates with worse neurological outcome in human patients. To date, there are no effective treatments to directly resolve edema within
Terese A. Garcia +2 more
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