Results 1 to 10 of about 69,793 (345)
Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes [PDF]
Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the ...
Irina Tsymala +23 more
doaj +5 more sources
Neuromyelitis optica pathogenesis and aquaporin 4 [PDF]
Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly features immunopathology in the optic nerves and the spinal cord.
Kerr Douglas +3 more
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Aquaporin 4 expression is downregulated in large bovine ovarian follicles
Aquaporin channels (AQPs) are known to play an important role in the development of ovarian follicles through their function in water transport pathways. Compared to other AQPs, research on the role of AQP4 in female reproductive physiology, particularly
Chang-Woon Kim +5 more
doaj +3 more sources
Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4 [PDF]
The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis ...
JW Snuggs, RAD Bunning, CL Le Maitre
doaj +1 more source
Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho +4 more
doaj +1 more source
Gonadal hormones and aquaporin-4: Preclinical insights into glymphatic regulation and amyloid clearance [PDF]
Muhammed Zahid Şahin +1 more
openalex +2 more sources
Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors. [PDF]
We analyzed aquaporin 4 and -1 expression in subependymomas, benign and slow growing brain tumors WHO grade I. Ten subependymoma cases were investigated, five of the fossa inferior and five of the fossa superior.Using immunohistochemistry, we observed ...
Susan Noell +5 more
doaj +1 more source
Background Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an effective treatment for reducing ...
Takuya Urushihata +9 more
doaj +1 more source
Brain aquaporin-4 expression in the rat septic model (immunohistochemical study)
The study aimed to determine aquaporin-4 expression in different brain regions was performed in Wistar rats subjected to cecal ligation and puncture (CLP) septic model.
T.V. Shulyatnikova, V.O. Tumanskiy
doaj +1 more source
Aquaporin-4 Expression in Meningioma Malignancy Progression
Objectives The aim of the present study is to analyze if aquaporin-4 (AQP4) may also be a tumor progression marker for meningiomas. Methods This is an immunohistochemistry study realized at the Universidade de São Paulo, São Paulo, state of ...
Benedito Jamilson Araújo Pereira +5 more
doaj +1 more source

