Results 1 to 10 of about 66,195 (165)
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance By studying paired blood and deep cervical lymph node samples from patients with neuromyelitis optica spectrum disorders, our data provide evidence for a germinal center–based generation of aquaporin-4 antibodies.
Valentina Damato +2 more
exaly +2 more sources
Desalination, 2017 Aquaporin plays a promising role in fabricating high performance biomimetic forward osmosis (FO) membranes. However, aquaporin as a protein also has a risk of denaturation caused by various chemicals, resulting in a possible decay of membrane performance.
Zhenyu Li +2 more
exaly +2 more sources
Frontiers in Pharmacology, 2022 In sickle cell disease (SCD), the pathological shift of red blood cells (RBCs) into distorted morphologies under hypoxic conditions follows activation of a cationic leak current (Psickle) and cell dehydration.
Pak Hin Chow +10 more
doaj +1 more source
Ravulizumab in Aquaporin‐4–Positive Neuromyelitis Optica Spectrum Disorder
Annals of Neurology, 2023 CHAMPION‐NMOSD (NCT04201262) is a phase 3, open‐label, externally controlled interventional study evaluating the efficacy and safety of the terminal complement inhibitor ravulizumab in adult patients with anti–aquaporin‐4 antibody–positive (AQP4 ...
S. Pittock +14 more
semanticscholar +1 more source
Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders.
Neurobiology of Disease, 2023 The clearance function is essential for maintaining brain tissue homeostasis, and the glymphatic system is the main pathway for removing brain interstitial solutes.
Shasha Peng +4 more
semanticscholar +1 more source
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis
Brain : a journal of neurology, 2021 Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at the glia limitans, where it mediates water exchange across the ...
M. Salman +8 more
semanticscholar +1 more source
Frontiers in Physiology, 2021 Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho +4 more
doaj +1 more source
Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression
Scientific Reports, 2021 Exposure to arsenic, a ubiquitous metalloid on Earth, results in human cancers. Skin cancer is the most common arsenical cancers. Both autophagy and aquaporin pathway are known to promote carcinogenesis. However, the mechanisms by which arsenic regulates
Sebastian Yu +5 more
doaj +1 more source
Exploring aquaporin functions during changes in leaf water potential
Frontiers in Plant Science, 2023 Maintenance of optimal leaf tissue humidity is important for plant productivity and food security. Leaf humidity is influenced by soil and atmospheric water availability, by transpiration and by the coordination of water flux across cell membranes ...
Caitlin S. Byrt +5 more
doaj +1 more source