Results 31 to 40 of about 57,369 (303)
Biotechnology & Biotechnological Equipment, 2017 Malignant pleural mesothelioma is a rare and fatal malignancy. This disease is, unfortunately, at its advanced stage when it is diagnosed. Survival time is usually not more than a few months.
Ulaş Alabalık +5 more
doaj +1 more source
Genome biology, 2006 Water is the major component of all living cells, and efficient regulation of water homeostasis is essential for many biological processes. The mechanism by which water passes through biological membranes was a matter of debate until the discovery of the aquaporin water channels.
Kruse, E, Uehlein, N, Kaldenhoff, R
openaire +3 more sources
Kidney International, 1996 Aquaporins (AQPs) are a newly recognized family of transmembrane proteins that function as molecular water channels. At least four aquaporins are expressed in the kidney where they mediate rapid water transport across water-permeable epithelia and play critical roles in urinary concentrating and diluting processes.
Knepper, Mark A. +8 more
openaire +2 more sources
Cells, 2023 [Aquaporins (AQPs) are a family of transmembrane channel proteins, widespread...]
openaire +4 more sources
Journal of Pharmacological Sciences, 2004 The discovery of the water channel aquaporin has greatly expanded our understanding of the regulation of the water permeability of biological membranes.
Masato Yasui
doaj +1 more source
Boric acid transport activity of marine teleost aquaporins expressed in Xenopus oocytes
Physiological Reports, 2023 Marine teleosts ingest large amounts of seawater containing various ions, including 0.4 mM boric acid, which can accumulate at toxic levels in the body. However, the molecular mechanisms by which marine teleosts absorb and excrete boric acid are not well
Shiori Kumagai +15 more
doaj +1 more source
Rinsho Shinkeigaku, 2008 In human body, there are thirteen water channels but their expression patterns are tissue specific. Aquaporin-4 (AQP4) is a predominantly expressed water channel in the mammalian brain and an important drug target for treatment of cerebral edema, bipolar disorder, and mesial temporal lobe epilepsy.
Tani, Kazutoshi +2 more
openaire +3 more sources
Aquaporin-4 gene silencing protects injured neurons after early cerebral infarction
Neural Regeneration Research, 2015 Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction.
Zhan-ping He, Hong Lu
doaj +1 more source
eLife, 2020 Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively selected for increased pore size from a common ancestor aquaporin.
Ali H Alghamdi +34 more
doaj +1 more source
, 2020 Review on aquaporin-2 (AQP2), with data on DNA, on the protein encoded, and where the gene is ...
Huret, Jean-Loup
core +1 more source