Results 51 to 60 of about 77,865 (353)

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Structure and Function of Aquaporins

open access: yesJournal of Pharmacological Sciences, 2004
The discovery of the water channel aquaporin has greatly expanded our understanding of the regulation of the water permeability of biological membranes.
Masato Yasui
doaj   +1 more source

Boric acid transport activity of marine teleost aquaporins expressed in Xenopus oocytes

open access: yesPhysiological Reports, 2023
Marine teleosts ingest large amounts of seawater containing various ions, including 0.4 mM boric acid, which can accumulate at toxic levels in the body. However, the molecular mechanisms by which marine teleosts absorb and excrete boric acid are not well
Shiori Kumagai   +15 more
doaj   +1 more source

Preparative scale production of functional mouse aquaporin 4 using different cell-free expression modes

open access: yes, 2010
The continuous progress in the structural and functional characterization of aquaporins increasingly attracts attention to study their roles in certain mammalian diseases.
Volker Dötsch   +23 more
core   +1 more source

Data_Sheet_1_Deep learning-based relapse prediction of neuromyelitis optica spectrum disorder with anti-aquaporin-4 antibody.pdf

open access: yes, 2022
ObjectiveWe previously identified the independent predictors of recurrent relapse in neuromyelitis optica spectrum disorder (NMOSD) with anti-aquaporin-4 antibody (AQP4-ab) and designed a nomogram to estimate the 1- and 2-year relapse-free probability ...
Yuanqi Zhao (677914)   +25 more
core   +1 more source

Aquaporin-4 gene silencing protects injured neurons after early cerebral infarction

open access: yesNeural Regeneration Research, 2015
Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction.
Zhan-ping He, Hong Lu
doaj   +1 more source

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

open access: yeseLife, 2020
Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively selected for increased pore size from a common ancestor aquaporin.
Ali H Alghamdi   +34 more
doaj   +1 more source

Expression and localization of Aquaporin 1a in the sea-bass (Dicentrarchus labrax) during ontogeny

open access: yes, 2011
The successful establishment of a species in a given habitat depends on the ability of each of its developing stages to adapt to the environment. In order to understand this process we have studied the adaptation of a euryhaline fish, the sea-bass ...
Guy Charmantier   +14 more
core   +1 more source

Aquaporin-4 expression in distal myopathy with rimmed vacuoles

open access: yesBMC Neurology, 2012
Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko   +5 more
doaj   +1 more source

Transcription profile and heterologous expression of Echinococcus granulosus aquaporins genes in the encysted protoscolex

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the role of Echinococcus granulosus aquaporins (EgAQPs) in the accumulation of hydatid fluid. Methods The secondary hydatids cultured in vitro and inoculated in BALB/c mice were collected respectively, and the relative transcription ...
TAN Qingqing   +4 more
doaj   +1 more source

Aquaporin‐Incorporated Graphene‐Oxide Membrane for Pressurized Desalination with Superior Integrity Enabled by Molecular Recognition

open access: yesAdvanced Science, 2021
Aquaporins (AQPs), the natural water channel, have been actively investigated for overcoming the limitations of conventional desalination membranes. An AQP‐based biomimetic high‐pressure desalination membrane is designed by tethering AQP‐carrying red ...
Chang Seon Lee   +4 more
doaj   +1 more source

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