The Role of Aquaporins in Spinal Cord Injury
Cells, 2023 Edema formation following traumatic spinal cord injury (SCI) exacerbates secondary injury, and the severity of edema correlates with worse neurological outcome in human patients. To date, there are no effective treatments to directly resolve edema within
Terese A. Garcia +2 more
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Aquaporin 4 as a NH3 Channel [PDF]
Journal of Biological Chemistry, 2016 Ammonia is a biologically potent molecule, and the regulation of ammonia levels in the mammalian body is, therefore, strictly controlled. The molecular paths of ammonia permeation across plasma membranes remain ill-defined, but the structural similarity of water and NH3 has pointed to the aquaporins as putative NH3-permeable pores. Accordingly, a range
Assentoft, Mette +5 more
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Mycoplasma pneumoniae infection and concurrent aquaporin-4-positive neuromyelitis optica spectrum disorder: a case report and literature review [PDF]
BMC PediatrHong Liang, Yu‐Wen Chen, Pi-Mei Zheng
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Neuromyelitis optica spectrum disorders with an inverted V sign on spinal cord magnetic resonance imaging: antiaquaporin-4 antibody and functional vitamin B12 deficiency [PDF]
Journal of Medicine and Life Science, 2022 Several studies have reported a possible link between antiaquaporin- 4 antibody and vitamin B12 deficiency in neuromyelitis optica spectrum disorder (NMOSD).
Sung Jo Bang +4 more
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Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]
, 2015 To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Asgari, Nasrin +4 more
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Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression [PDF]
Research Results in Pharmacology, 2022 Introduction: Morphine is an opioid prescribed to treat aches and pains. However, morphine often causes opioid-induced constipation (OIC). Aquaporin (AQP) transporters, especially AQP3 and AQP4, play an essential role in mediating constipation. Bisacodyl
Mahardian Rahmadi +9 more
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Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis [PDF]
, 2014 © 2014 Sridhar et al.; licensee BioMed Central Ltd.Background: Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and ...
Chan, JFW, Sridhar, S, Yuen, KY
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Barley plasma membrane intrinsic proteins (PIP aquaporins) as water and CO2 transporters [PDF]
, 2008 We identified barley aquaporins and demonstrated that one, HvPIP2;1, transports water and CO2. Regarding water homeostasis in plants, regulations of aquaporin expression were observed in many plants under several environmental stresses. Under salt stress,
C Zhu +33 more
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Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Stroke among Patients with Hypertension [PDF]
, 2020 Background: Dysregulations ofAQP7andAQP9were found to be related to lipid metabolism abnormality, which had been provento be one of the mechanisms of stroke. However, limited epidemiological studies explore the associations betweenAQP7andAQP9and the risk
Cui, Lan +6 more
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Aquaporin-4 gene silencing protects injured neurons after early cerebral infarction
Neural Regeneration Research, 2015 Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction.
Zhan-ping He, Hong Lu
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