Results 31 to 40 of about 38,816 (262)
Evaluation of aquaporin‐4 antibody assays [PDF]
Clinical and Experimental Neuroimmunology, 2014 AbstractAquaporin‐4 (AQP4) is a water channel protein that is most highly, but not exclusively, expressed in the central nervous system. In 2005 AQP4 was shown to be the antigenic target of neuromyelitis optica‐immunoglobulin G (NMO‐IgG, or AQP4‐IgG), an antibody found specifically in patients with NMO and in formes frustes of NMO, such as ...
Patrick J, Waters +5 more
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Journal of Medical Case Reports, 2019 Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot +6 more
doaj +1 more source
Primary Sjögren’s syndrome related optic neuritis
International Journal of Ophthalmology, 2013 AIM:To determine the clinical features, diagnosis and treatment of the primary Sjögren syndrome (SS) related optic neuritis.METHODS:The clinical data of 8 patients (12 eyes) with primary SS related optic neuritis were analyzed retrospectively.RESULTS ...
Wei-Qiang Tang, Shi-Hui Wei
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Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2018 Background The specificity of the aquaporin-4 antibody to predict recurrent inflammatory central nervous system disease has led to the design of the 2015 neuromyelitis optica spectrum disorder criteria which capture all aquaporin-4 antibody seropositive ...
M McCreary +5 more
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Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques [PDF]
Journal of Neuropathology & Experimental Neurology, 2020 Abstract Gerstmann-Sträussler-Scheinker (GSS) disease with P102L mutation and familial Creutzfeldt-Jakob disease (CJD) with V180I mutation are 2 major hereditary prion diseases in Japan. GSS and some familial CJD [V180I] exhibit characteristic prion protein (PrP) plaques. Overexpression of the astrocytic water channel proteins aquaporin (
Shoko Sadashima +7 more
openaire +2 more sources
Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus
Cerebrospinal Fluid Research, 2010 The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
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Integrative Medicine Research, 2019 An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst ...
Seungwon Kwon, Chul Jin, Ki-Ho Cho
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An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays. [PDF]
PLoS ONE, 2013 Cell-based assays (CBA) have increased the sensitivity of the neuromyelitis optica (NMO)-IgG/aquaporin-4-antibody detection compared to classical tissue-based indirect assays.
Romana Höftberger +10 more
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Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]
Medicinski PodmladakDiscovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko +2 more
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Frontiers in Pharmacology, 2022 Ischemic stroke (IS) has been associated with an impairment in glymphatic function. Xuefu Zhuyu Decoction (XFZYD) is widely used in the prevention and treatment of ischemic stroke.
Ting Yi +13 more
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