Results 51 to 60 of about 12,794,158 (296)

Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques [PDF]

Journal of Neuropathology & Experimental Neurology, 2020
Abstract Gerstmann-Sträussler-Scheinker (GSS) disease with P102L mutation and familial Creutzfeldt-Jakob disease (CJD) with V180I mutation are 2 major hereditary prion diseases in Japan. GSS and some familial CJD [V180I] exhibit characteristic prion protein (PrP) plaques. Overexpression of the astrocytic water channel proteins aquaporin (
Shoko Sadashima, Hiroyuki Honda, Satoshi O Suzuki, Masahiro Shijo, Shinichi Aishima, Keita Kai, Junichi Kira, Toru Iwaki   +7 more
openaire   +2 more sources

Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus

Cerebrospinal Fluid Research, 2010
The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
doaj   +1 more source

An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review

Integrative Medicine Research, 2019
An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst ...
Seungwon Kwon, Chul Jin, Ki-Ho Cho
doaj   +1 more source

Gas-tight triblock-copolymer membranes are converted to CO2 permeable by insertion of plant aquaporins [PDF]

, 2012
We demonstrate that membranes consisting of certain triblock-copolymers were tight for CO2. Using a novel approach, we provide evidence for aquaporin facilitated CO2 diffusion.
Itel, Fabian, Otto, B., Uehlein, N., Uehlein, Norbert, Kaldenhoff, Ralf, Itel, F., Otto, Beate, Meier, W., Kaldenhoff, R., Meier, Wolfgang, Eilingsfeld, A., Eilingsfeld, Adrian   +11 more
core   +1 more source

Data_Sheet_1_Deep learning-based relapse prediction of neuromyelitis optica spectrum disorder with anti-aquaporin-4 antibody.pdf

, 2022
ObjectiveWe previously identified the independent predictors of recurrent relapse in neuromyelitis optica spectrum disorder (NMOSD) with anti-aquaporin-4 antibody (AQP4-ab) and designed a nomogram to estimate the 1- and 2-year relapse-free probability ...
Yuanqi Zhao (677914), Wenjuan Huang (707703), Qiang Dong (380835), Lei Zhou (19808), Junhui Xia (12324599), Jianhua Ma (486317), Lei Du (14992), Bei Wang (116772), Fang Li (41162), Chongbo Zhao (4705297), Chao Quan (449518), Jie Yang (121778), Jingzi ZhangBao (10308230), Liang Wang (23021), Xuechun Chang (10308227), Wenyu Li (455531), Chuanzhen Lu (168918), Qinying Li (721250), Qiang Meng (2853221), Hongmei Tan (4533502), Min Wang (21070), Jiahong Lu (4330093), Heng Li (6476), Jian Yu (141239), Juyuan Pan (12324596), Shitao Wu (8769479)   +25 more
core   +1 more source

Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]

Medicinski Podmladak
Discovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko, Drulović Jelena, Novaković Ivana   +2 more
doaj   +1 more source

An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays. [PDF]

PLoS ONE, 2013
Cell-based assays (CBA) have increased the sensitivity of the neuromyelitis optica (NMO)-IgG/aquaporin-4-antibody detection compared to classical tissue-based indirect assays.
Romana Höftberger, Lidia Sabater, Romain Marignier, Fahmy Aboul-Enein, Raphaël Bernard-Valnet, Helmut Rauschka, Anne Ruiz, Yolanda Blanco, Francesc Graus, Josep Dalmau, Albert Saiz   +10 more
doaj   +1 more source

Aquaporin-4 Autoantibodies in a Paraneoplastic Context [PDF]

Archives of Neurology, 2008
The neuromyelitis optica IgG autoantibody (NMO-IgG) is a validated biomarker for NMO and an emerging spectrum of inflammatory central nervous system-demyelinating disorders. Its antigen is the astrocytic water channel aquaporin-4; NMO-IgG has not been described in a cancer context.To report (1) neurologic and oncologic correlates for patients ...
Sean J, Pittock, Vanda A, Lennon
openaire   +2 more sources

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Khorooshi, Reza; id_orcid, Mørch, Marlene Thorsen, Owens, Trevor; id_orcid, Berg, Carsten Tue, Asgari, Nasrin   +4 more
core   +1 more source

The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

Frontiers in Pharmacology, 2022
Ischemic stroke (IS) has been associated with an impairment in glymphatic function. Xuefu Zhuyu Decoction (XFZYD) is widely used in the prevention and treatment of ischemic stroke.
Ting Yi, Ping Gao, Meng Hou, Huan Lv, Mengyuan Huang, Shanshan Gao, Jinrong He, Dongdong Yang, Weiyin Chen, Tianmin Zhu, Chang Yu, Fuyou Liu, Haiyan Yin, Shuoguo Jin   +13 more
doaj   +1 more source