Co-occurrence of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder and hepatocellular carcinoma: A case report [PDF]
Journal of International Medical ResearchNeuromyelitis optica spectrum disorder is a rare, relapsing autoimmune disease in which the immune system attacks the central nervous system, primarily the optic nerves and spinal cord.
Cheng Li, Weijing Liao, Di Long
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Recurrent aquaporin 4-immunoglobulin G-positive neuromyelitis optica spectrum disorder in a patient with long-standing rheumatoid arthritis: A case report [PDF]
Journal of International Medical ResearchNeuromyelitis optica spectrum disorder is an autoimmune astrocytopathy that primarily affects the optic nerves and spinal cord. Its association with rheumatoid arthritis is remarkably rare, with only 15 documented cases reported globally to date.
Xuechun Jiang +4 more
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Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4 [PDF]
European Cells & Materials, 2021 The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis ...
JW Snuggs, RAD Bunning, CL Le Maitre
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Frontiers in Physiology, 2021 Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho +4 more
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Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors. [PDF]
PLoS ONE, 2015 We analyzed aquaporin 4 and -1 expression in subependymomas, benign and slow growing brain tumors WHO grade I. Ten subependymoma cases were investigated, five of the fossa inferior and five of the fossa superior.Using immunohistochemistry, we observed ...
Susan Noell +5 more
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Diagnostic utility of aquaporin-4 blood level in neonatal hypoxic ischemic encephalopathy [PDF]
Zagazig University Medical Journal, 2023 Background: In neonates, cerebral hypoxic-ischemia is the main cause of brain oedema which results in neurodevelopmental disfunction. After cerebral injury, Aquaporin-4 (AQP4) is reported to be overexpressed in the astrocytes. This study was conducted to
Ehab Elbanna +3 more
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Brain aquaporin-4 expression in the rat septic model (immunohistochemical study)
Medičnì Perspektivi, 2022 The study aimed to determine aquaporin-4 expression in different brain regions was performed in Wistar rats subjected to cecal ligation and puncture (CLP) septic model.
T.V. Shulyatnikova, V.O. Tumanskiy
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European Radiology Experimental, 2021 Background Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an effective treatment for reducing ...
Takuya Urushihata +9 more
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Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes
Acta Neuropathologica Communications, 2020 Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the ...
Irina Tsymala +23 more
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Genetic deletion of laminin isoforms β2 and γ3 induces a reduction in Kir4.1 and aquaporin-4 expression and function in the retina. [PDF]
PLoS ONE, 2011 Glial cells such as retinal Müller glial cells are involved in potassium ion and water homeostasis of the neural tissue. In these cells, inwardly rectifying potassium (Kir) channels and aquaporin-4 water channels play an important role in the process of ...
Petra G Hirrlinger +8 more
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