Results 11 to 20 of about 26,122,743 (292)
Aquaporin 4: a player in cerebral edema and neuroinflammation [PDF]
Journal of Neuroinflammation, 2012 Neuroinflammation is a common pathological event observed in many different brain diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by cerebral edema.
Fukuda Andrew M, Badaut Jerome
doaj +6 more sources
Aquaporin-4 and Cognitive Disorders
Aging and disease, 2022 Aquaporin-4 (AQP4) is the most abundantly expressed aquaporin in the central nervous system (CNS) and is an integral part of the glymphatic system that cannot be ignored. The CNS has the glymphatic system instead of the conventional lymphatic system. The
Yifan Wang +3 more
semanticscholar +3 more sources
Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes [PDF]
Acta Neuropathologica Communications, 2020 Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the ...
Irina Tsymala +23 more
doaj +4 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Review on AQP4 (aquaporin 4), with data on DNA, on the protein encoded, and where the gene is implicated.
RIBATTI, Domenico, NICO, Beatrice
openaire +4 more sources
Aquaporin-4 expression in distal myopathy with rimmed vacuoles [PDF]
BMC Neurology, 2012 Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko +5 more
doaj +3 more sources
Aquaporin-4 and Parkinson’s Disease
International Journal of Molecular SciencesThe water-selective channel aquaporin-4 (AQP4) is implicated in water homeostasis and the functioning of the glymphatic system, which eliminates various metabolites from the brain tissue, including amyloidogenic proteins.
Ksenia V. Lapshina, I. Ekimova
semanticscholar +3 more sources
Neuromyelitis optica pathogenesis and aquaporin 4 [PDF]
Journal of Neuroinflammation, 2008 Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly features immunopathology in the optic nerves and the spinal cord.
Kerr Douglas +3 more
doaj +3 more sources
Aquaporin-4 gene silencing protects injured neurons after early cerebral infarction
Neural Regeneration Research, 2015 Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction.
Zhan-ping He, Hong Lu
doaj +2 more sources
Skull diploë is rich in aquaporin-4 [PDF]
Heliyon, 2020 Aquaporin-4 (AQP4) is a water conducting membrane integral protein channel which is widely expressed in the astrocyte system of the brain. During the development of the AQP4 positron emission tomography (PET) imaging agent [11C]TGN-020 (N-(1,3,4 ...
Yuji Suzuki +7 more
doaj +3 more sources
Aquaporin-4 in hepatic encephalopathy
Metabolic Brain Disease, 2007 Brain edema is a critical component of hepatic encephalopathy (HE) associated with acute liver failure and such edema appears to be principally due to astrocyte swelling (cytotoxic edema). Ammonia is believed to represent a major factor responsible for astrocyte swelling, although the mechanisms by which ammonia causes such swelling are not completely ...
K V, Rama Rao, M D, Norenberg
openaire +3 more sources