Results 31 to 40 of about 38,738 (164)
Primary Sjögren’s syndrome related optic neuritis
International Journal of Ophthalmology, 2013 AIM:To determine the clinical features, diagnosis and treatment of the primary Sjögren syndrome (SS) related optic neuritis.METHODS:The clinical data of 8 patients (12 eyes) with primary SS related optic neuritis were analyzed retrospectively.RESULTS ...
Wei-Qiang Tang, Shi-Hui Wei
doaj +1 more source
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2018 Background The specificity of the aquaporin-4 antibody to predict recurrent inflammatory central nervous system disease has led to the design of the 2015 neuromyelitis optica spectrum disorder criteria which capture all aquaporin-4 antibody seropositive ...
M McCreary +5 more
doaj +1 more source
Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus
Cerebrospinal Fluid Research, 2010 The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
doaj +1 more source
Integrative Medicine Research, 2019 An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst ...
Seungwon Kwon, Chul Jin, Ki-Ho Cho
doaj +1 more source
An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays. [PDF]
PLoS ONE, 2013 Cell-based assays (CBA) have increased the sensitivity of the neuromyelitis optica (NMO)-IgG/aquaporin-4-antibody detection compared to classical tissue-based indirect assays.
Romana Höftberger +10 more
doaj +1 more source
Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]
Medicinski PodmladakDiscovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko +2 more
doaj +1 more source
Aquaporin-4 Autoantibodies in a Paraneoplastic Context [PDF]
Archives of Neurology, 2008 The neuromyelitis optica IgG autoantibody (NMO-IgG) is a validated biomarker for NMO and an emerging spectrum of inflammatory central nervous system-demyelinating disorders. Its antigen is the astrocytic water channel aquaporin-4; NMO-IgG has not been described in a cancer context.To report (1) neurologic and oncologic correlates for patients ...
Sean J, Pittock, Vanda A, Lennon
openaire +2 more sources
Frontiers in Pharmacology, 2022 Ischemic stroke (IS) has been associated with an impairment in glymphatic function. Xuefu Zhuyu Decoction (XFZYD) is widely used in the prevention and treatment of ischemic stroke.
Ting Yi +13 more
doaj +1 more source
Physiological Roles of Aquaporin-4 in Brain
Physiological Reviews, 2013 Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While AQP4 has been implicated in a number of pathophysiological processes, its role in brain physiology has remained elusive.
Erlend A, Nagelhus, Ole P, Ottersen
openaire +3 more sources
Aquaporin 4: a player in cerebral edema and neuroinflammation
Journal of Neuroinflammation, 2012 Neuroinflammation is a common pathological event observed in many different brain diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by cerebral edema.
Fukuda Andrew M, Badaut Jerome
doaj +1 more source