Results 41 to 50 of about 99,139,021 (297)

Neuromyelitis optica spectrum disorders with an inverted V sign on spinal cord magnetic resonance imaging: antiaquaporin-4 antibody and functional vitamin B12 deficiency [PDF]

Journal of Medicine and Life Science, 2022
Several studies have reported a possible link between antiaquaporin- 4 antibody and vitamin B12 deficiency in neuromyelitis optica spectrum disorder (NMOSD).
Sung Jo Bang, Sohyeon Kim, Young Seok Jeong, Seo Hyeon Lee, Hung Youl Seok   +4 more
doaj   +1 more source

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Khorooshi, Reza; id_orcid, Mørch, Marlene Thorsen, Owens, Trevor; id_orcid, Berg, Carsten Tue, Asgari, Nasrin   +4 more
core   +1 more source

Neuromyelitis optica spectrum disorder with increased aquaporin-4 microparticles prior to autoantibodies in cerebrospinal fluid: a case report

Journal of Medical Case Reports, 2019
Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot, Eva Hesselmark, Fariborz Mobarrez, Håkan Wallén, Max Albert Hietala, Rolf Nybom, Lennart Wetterberg   +6 more
doaj   +1 more source

Primary Sjögren’s syndrome related optic neuritis

International Journal of Ophthalmology, 2013
AIM:To determine the clinical features, diagnosis and treatment of the primary Sjögren syndrome (SS) related optic neuritis.METHODS:The clinical data of 8 patients (12 eyes) with primary SS related optic neuritis were analyzed retrospectively.RESULTS ...
Wei-Qiang Tang, Shi-Hui Wei
doaj   +1 more source

Updated diagnostic criteria for neuromyelitis optica spectrum disorder: Similar outcomes of previously separate cohorts

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2018
Background The specificity of the aquaporin-4 antibody to predict recurrent inflammatory central nervous system disease has led to the design of the 2015 neuromyelitis optica spectrum disorder criteria which capture all aquaporin-4 antibody seropositive ...
M McCreary, MA Mealy, DM Wingerchuk, M Levy, A DeSena, BM Greenberg   +5 more
doaj   +1 more source

Concentrations of B cell-activating factor, aquaporin-4 antibody and brain-derived neurotrophic factor in neuromyelitis optica spectrum disorder

Türk Biyokimya Dergisi, 2022
To explore the correlations of B cell-activating factor (BAFF), aquaporin-4 antibody (AQP4-Ab) and brain-derived neurotrophic factor (BDNF) with the severity of neuromyelitis optica spectrum disorder (NMOSD).
Li Suping, Fu Jing, Xu Fei, Yu Liang, Yu Qian, Yu Nengwei   +5 more
doaj   +1 more source

Aquaporin Expression Contributes to Human Transurothelial Permeability In Vitro and Is Modulated by NaCl [PDF]

, 2012
It is generally considered that the bladder is impervious and stores urine in unmodified form on account of the barrier imposed by the highly-specialised uro-epithelial lining.
Lisa A Kirkwood, Kirkwood Lisa A., Rubenwolf, Peter C., Jennifer Southgate, Georgopoulos, Nikolaos T., Georgopoulos Nikolaos T., Rubenwolf Peter C., Kirkwood, Lisa A., Baker Simon C., Peter C Rubenwolf, Southgate, Jennifer, Southgate Jennifer, Baker, Simon C., Simon C Baker, Nikolaos T Georgopoulos   +14 more
core   +2 more sources

Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus

Cerebrospinal Fluid Research, 2010
The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
doaj   +1 more source

Alleviation of Cerebral Infarction of Rats With Middle Cerebral Artery Occlusion by Inhibition of Aquaporin 4 in the Supraoptic Nucleus

ASN Neuro, 2020
In ischemic stroke, vasopressin hypersecretion is a critical factor of cerebral swelling and brain injury. To clarify neural mechanisms underlying ischemic stroke-evoked vasopressin hypersecretion, we observed the effect of unilateral permanent middle ...
Dan Cui, Shuwei Jia, Jiawei Yu, Dongyang Li, Tong Li, Yang Liu, Jinlong Chang, Xiaoran Wang, Xiaoyu Liu, Yu-Feng Wang   +9 more
doaj   +1 more source

The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

Frontiers in Pharmacology, 2022
Ischemic stroke (IS) has been associated with an impairment in glymphatic function. Xuefu Zhuyu Decoction (XFZYD) is widely used in the prevention and treatment of ischemic stroke.
Ting Yi, Ping Gao, Meng Hou, Huan Lv, Mengyuan Huang, Shanshan Gao, Jinrong He, Dongdong Yang, Weiyin Chen, Tianmin Zhu, Chang Yu, Fuyou Liu, Haiyan Yin, Shuoguo Jin   +13 more
doaj   +1 more source