Results 61 to 70 of about 38,738 (164)
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective To explore the distribution characteristics of aquaporin 4 (AQP4) antibody in serum and cerebrospinal fluid (CSF) of neuromyelitis optica (NMO) patients, and to analyze the relationship between AQP4 antibody and oligoclonal bands (OB) in CSF
Hui-cong NIU, Xing-hu ZHANG
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Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
Journal of Neuroinflammation, 2018 Background Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement ...
Tianjiao Duan +2 more
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Aquaporin 4 Expression in the mdx Mouse Diaphragm
ACTA HISTOCHEMICA ET CYTOCHEMICA, 2011 Expression of aquaporin (AQP) 4 in the surface membranes of skeletal myofibers is well established; however, its functional significance is still unknown. The alterations of AQP4 expressions in dystrophic muscles at RNA and protein levels have been reported in various dystrophic muscles such as dystrophinopathy, dysferlinopathy, and sarcoglycanopathy ...
Hara, Hajime +6 more
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Detection and clinical value of NMO-IgG in neuromyelitis optica
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system (CNS) of autoimmune etiology which predominantly affects the optic nerves and spinal cord.
De-hui HUANG, Wei-ping WU
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Fluids and Barriers of the CNSCerebrospinal fluid (CSF) enters the brain along perivascular spaces in a manner that depends on aquaporin-4 (AQP4) polarization, facilitating brain clearance and is called the glymphatic system.
Chenchen Liu +8 more
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The developmental history of study on neuromyelitis optica
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 In 19th century, neuromyelitis optica (NMO) indicated optic neuritis and myelitis with simultaneous onset of both sides. Later studies proposed that the onset of right or left side optic neuritis could be separated by weeks, months even years.
Kai FENG, Xing-hu ZHANG, Xian-hao XU
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Neural Regeneration ResearchNeuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction. To date, no effective treatment exists as the exact causative mechanism remains unknown.
Li Xu, Huiming Xu, Changyong Tang
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Medicina, 2014 Disease-specific aquaporin-4 antibodies (NMO-IgG) are the main effector of lesions in neuromyelitis optica (NMO) patients. Brain MRI lesions are detected in 60% of them, with 8% (almost infants) at sites of high aquaporin-4 expression. Patient 1: A fifty-year-old male with loss of vision in the right eye.
Alejandra, Báez +5 more
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Investigating the Association between Aquaporin-4 and Osteoporosis in Patients with Neuromyelitis Optica Spectrum Disorders [PDF]
پیاورد سلامتBackground and Aim: Neuromyelitis Optica Spectrum Disorders (NMOSD) is an uncommon disorder of the central nervous system mainly affecting the optic nerves and spinal cord. NMOSD is associated with IgG antibody binding to aquaporin-4 (AQP4) that triggers
Zhila Maghbooli +3 more
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