Results 41 to 50 of about 85,347,708 (300)

Evaluation of aquaporin‐4 antibody assays [PDF]

open access: yesClinical and Experimental Neuroimmunology, 2014
AbstractAquaporin‐4 (AQP4) is a water channel protein that is most highly, but not exclusively, expressed in the central nervous system. In 2005 AQP4 was shown to be the antigenic target of neuromyelitis optica‐immunoglobulin G (NMO‐IgG, or AQP4‐IgG), an antibody found specifically in patients with NMO and in formes frustes of NMO, such as ...
Patrick J, Waters   +5 more
openaire   +2 more sources

Neuromyelitis optica spectrum disorder with increased aquaporin-4 microparticles prior to autoantibodies in cerebrospinal fluid: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot   +6 more
doaj   +1 more source

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

open access: yes, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Khorooshi, Reza; id_orcid   +4 more
core   +1 more source

the-effect-of-the-administration-of-minosycline-n-acetyl-systein-and-its-combinations-on-aquaporin-4-expression-in-the-brain-of-treated-brain-injury-mice-62bd269672899.pdf

open access: yes, 2023
 Brain injuries are serious health problems and require appropriate management strategies in the healing process. The purpose of this research was to determine the effect of minocycline and single N-Acetylcysteine compared to the administration of a ...
Farhad Balafif (15189535)
core   +1 more source

Primary Sjögren’s syndrome related optic neuritis

open access: yesInternational Journal of Ophthalmology, 2013
AIM:To determine the clinical features, diagnosis and treatment of the primary Sjögren syndrome (SS) related optic neuritis.METHODS:The clinical data of 8 patients (12 eyes) with primary SS related optic neuritis were analyzed retrospectively.RESULTS ...
Wei-Qiang Tang, Shi-Hui Wei
doaj   +1 more source

Updated diagnostic criteria for neuromyelitis optica spectrum disorder: Similar outcomes of previously separate cohorts

open access: yesMultiple Sclerosis Journal - Experimental, Translational and Clinical, 2018
Background The specificity of the aquaporin-4 antibody to predict recurrent inflammatory central nervous system disease has led to the design of the 2015 neuromyelitis optica spectrum disorder criteria which capture all aquaporin-4 antibody seropositive ...
M McCreary   +5 more
doaj   +1 more source

Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques [PDF]

open access: yesJournal of Neuropathology & Experimental Neurology, 2020
Abstract Gerstmann-Sträussler-Scheinker (GSS) disease with P102L mutation and familial Creutzfeldt-Jakob disease (CJD) with V180I mutation are 2 major hereditary prion diseases in Japan. GSS and some familial CJD [V180I] exhibit characteristic prion protein (PrP) plaques. Overexpression of the astrocytic water channel proteins aquaporin (
Shoko Sadashima   +7 more
openaire   +2 more sources

Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus

open access: yesCerebrospinal Fluid Research, 2010
The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
doaj   +1 more source

Aquaporin Expression Contributes to Human Transurothelial Permeability In Vitro and Is Modulated by NaCl [PDF]

open access: yes, 2012
It is generally considered that the bladder is impervious and stores urine in unmodified form on account of the barrier imposed by the highly-specialised uro-epithelial lining.
Lisa A Kirkwood   +14 more
core   +2 more sources

An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review

open access: yesIntegrative Medicine Research, 2019
An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst ...
Seungwon Kwon, Chul Jin, Ki-Ho Cho
doaj   +1 more source

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