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Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries

open access: yesJournal of Experimental Medicine, 2017
Reactive remodeling of optic nerve head astrocytes is consistently observed in glaucoma and other optic nerve injuries. However, it is unknown whether this reactivity is beneficial or harmful for visual function.
Tatjana Jakobs, Daniel Sun
exaly   +2 more sources

Optic nerve as a source of activated retinal microglia post-injury

open access: yesActa Neuropathologica Communications, 2018
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons.
Neal D. Heuss   +6 more
doaj   +2 more sources

Behaviour of Disc Oedema During and After Amiodarone Optic Neuropathy: Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
A 73-year-old woman with atrial fibrillation treated with Amiodarone presented with Optic Disc oedema in right eye (OD). Using Optical Coherence Tomography (OCT) we describe the impact of this neuropathy on Retinal Nerve Fibre Layer (RNFL). At diagnosis
Med. Alejandro Martínez-López-Portillo   +4 more
doaj   +1 more source

Two-year outcomes of ab interno trabeculectomy with the Trabectome for Chinese primary open angle glaucoma: a retrospective multicenter study [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To evaluate the 2-year efficacy and safety of ab interno trabeculectomy with the Trabectome in Chinese primary open angle glaucoma (POAG) patients. METHODS: This was a multicenter, retrospective, observational study and included POAG patients with ...
Ya-Long Dang   +7 more
doaj   +1 more source

Bilateral calcification of the optic nerve sheath: A diagnostic dilemma

open access: yesAmerican Journal of Ophthalmology Case Reports, 2021
Purpose: To present a case of symptomatic optic nerve sheath calcification and highlight clues and pitfalls for the final diagnosis: bilateral optic nerve sheath meningioma.
Yngvil Solheim Husum   +6 more
doaj   +1 more source

Optic Nerve Hypoplasia

open access: yesDefinitions, 2020
This datasheet on optic nerve hypoplasia covers Identity, Hosts/Species Affected, Diagnosis.
M. El-Dairi, Robert J. House
semanticscholar   +1 more source

Computed Tomography Density and β-Amyloid Deposition of Intraorbital Optic Nerve May Assist in Diagnosing Mild Cognitive Impairment and Alzheimer’s Disease: A 18F-Flutemetamol Positron Emission Tomography/Computed Tomography Study

open access: yesFrontiers in Aging Neuroscience, 2022
ObjectiveThe aim was to study whether the computed tomography (CT) density and β-amyloid (Aβ) level of intraorbital optic nerve could assist in diagnosing mild cognitive impairment (MCI) and Alzheimer’s disease (AD).MethodsA total of sixty subjects were ...
Han Wu   +16 more
doaj   +1 more source

Computational approaches for the reconstruction of optic nerve fibers along the visual pathway from medical images: a comprehensive review

open access: yesFrontiers in Neuroscience, 2023
Optic never fibers in the visual pathway play significant roles in vision formation. Damages of optic nerve fibers are biomarkers for the diagnosis of various ophthalmological and neurological diseases; also, there is a need to prevent the optic nerve ...
Richu Jin   +11 more
doaj   +1 more source

Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review

open access: yesFrontiers in Oncology, 2021
Optic nerve hemangioblastoma is a very rare benign tumor with only 39 reported cases by now. It appears to be hyperintense on T2-weighted images with a significant enhancement on contrast scans, which are similar to glioma and meningioma. Due to the lack
Meihan Duan   +5 more
doaj   +1 more source

Atypical acute presentation of an optic nerve sheath meningioma

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: Primary optic nerve sheath meningiomas (ONSM) are benign lesions that typically present with findings of painless proptosis (59%), optic nerve pallor (55%), and decreased peripheral vision (35%). Herein we share an atypical case of a patient who
Cole Holan   +3 more
doaj   +1 more source

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