Photopic negative response recorded with RETeval system in eyes with optic nerve disorders
Scientific Reports, 2022 Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases.
Tsutomu Yamashita +7 more
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Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases
Brain Sciences, 2023 Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng +4 more
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NRF2 Deficiency Disrupts Mitochondrial Homeostasis via NDUFS7 in Trabecular Meshwork
ResearchThe trabecular meshwork (TM) plays a pivotal role in maintaining intraocular pressure (IOP) by regulating aqueous humor outflow. Nuclear factor erythroid 2-related factor 2 (NRF2) was identified as a key transcriptional controller of TM redox balance and
Xuejing Yan +6 more
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Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]
, 2009 NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S. +8 more
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Mechanical activation of PIEZO1 drives AP-1–dependent PTGS2/PGE2 signaling and corneal inflammation
iScienceSummary: Abnormal mechanical stimulation, such as eye rubbing, is a critical risk factor for corneal diseases, yet the molecular mechanisms linking mechanical stimulation to inflammation remain unclear.
Zongzheng Zou +10 more
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Molecular Therapy: Methods & Clinical DevelopmentAdeno-associated viral (AAV) vectors are being used increasingly in developing treatments for age-related ocular diseases, including those impacting retinal ganglion cells (RGCs), the output neurons of the eye.
Delaney CM. Henderson +1 more
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Development of a novel model of optic neuritis to assess neuroprotective and repair strategies in multiple sclerosis [PDF]
, 2012 PhDMultiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS), which often affects the optic nerve pathway. Optic neuritis (ON) is a clinical feature of MS that can cause loss of vision due to conduction block and ...
Lidster, Katie
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The thickness of the retrobulbar portion of the optic nerve in Graves ophthalmopathy measured by ultrasound [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 Introduction. The clinical diagnostic of Graves ophthalmopathy is based on the association of ocular signs and the disease of the thyroid gland. The evolution of the disease involves the development of eye globe protrusion, extraocular muscle thickening ...
Stefanović Ivan +3 more
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Frontiers in Bioengineering and BiotechnologyPurposeTo characterize the spatiotemporal evolution of corneal biomechanical properties after corneal cross-linking (CXL) using optical coherence elastography (OCE), with particular emphasis on regional changes in a hemicorneal partial-CXL model and ...
Yuqi Liu +9 more
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Postnatal development of the optic nerve in (C57BL x CBA)F1 hybrid mice:general changes in morphometric parameters [PDF]
, 1996 A morphometric analysis of the optic nerve in different age groups of (C57BL x CBA)F1 hybrid mice was carried out. Morphometric parameters examined were mean nerve cross-sectional area (csa), mean myelinated nerve fibre count, mean myelinated nerve fibre
Dangata, Y Y +2 more
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