Results 21 to 30 of about 639,989 (212)

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

open access: yes, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S.   +8 more
core   +1 more source

Photopic negative response recorded with RETeval system in eyes with optic nerve disorders

open access: yesScientific Reports, 2022
Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases.
Tsutomu Yamashita   +7 more
doaj   +1 more source

Metastatic optic nerve sheath calcification with optic atrophy associated with untreated hyperparathyroidism

open access: yesInterdisciplinary Neurosurgery, 2020
Background: To date, the etiology of optic nerve sheath calcifications is unclear and visual loss secondary to optic nerve sheath calcifications has been reported infrequently.
Patrick K. Jowdy   +2 more
doaj   +1 more source

Hemangioblastoma of the optic nerve [PDF]

open access: yesSurvey of Ophthalmology, 2019
Optic nerve hemangioblastoma is a rare tumor that is usually unilateral and most commonly occurs in the context of von Hippel-Lindau disease. Differential diagnosis is based on clinical history and imaging. Magnetic resonance imaging with gadolinium enhancement is the most useful imaging modality as it can reveal flow voids and an absence of dural ...
Lindsay A. McGrath   +2 more
openaire   +5 more sources

Age effect on retina and optic disc normal values [PDF]

open access: yes, 2005
Purpose: To investigate retinal thickness and optic disc parameters by the Retinal Thickness Analyzer (RTA) glaucoma program in older normal subjects and to determine any age effect.
Chryssafis, C.   +5 more
core   +1 more source

Perioptic Cerebrospinal Fluid Dynamics in Idiopathic Intracranial Hypertension

open access: yesFrontiers in Neurology, 2018
Purpose: To examine the cerebrospinal fluid (CSF) dynamics along the entire optic nerve in patients with idiopathic intracranial hypertension (IIH) and papilledema by computed tomographic (CT) cisternography.Methods: Retrospective analysis of CT ...
Achmed Pircher   +6 more
doaj   +1 more source

The Biomechanics of Indirect Traumatic Optic Neuropathy Using a Computational Head Model With a Biofidelic Orbit

open access: yesFrontiers in Neurology, 2020
Indirect traumatic optic neuropathy (ITON) is an injury to the optic nerve due to head trauma and usually results in partial or complete loss of vision. In order to advance a mechanistic understanding of the injury to the optic nerve, we developed a head
Yang Li   +6 more
doaj   +1 more source

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

open access: yesBrain Sciences, 2023
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng   +4 more
doaj   +1 more source

NRF2 Deficiency Disrupts Mitochondrial Homeostasis via NDUFS7 in Trabecular Meshwork

open access: yesResearch
The trabecular meshwork (TM) plays a pivotal role in maintaining intraocular pressure (IOP) by regulating aqueous humor outflow. Nuclear factor erythroid 2-related factor 2 (NRF2) was identified as a key transcriptional controller of TM redox balance and
Xuejing Yan   +6 more
doaj   +1 more source

Mechanical activation of PIEZO1 drives AP-1–dependent PTGS2/PGE2 signaling and corneal inflammation

open access: yesiScience
Summary: Abnormal mechanical stimulation, such as eye rubbing, is a critical risk factor for corneal diseases, yet the molecular mechanisms linking mechanical stimulation to inflammation remain unclear.
Zongzheng Zou   +10 more
doaj   +1 more source

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