Results 31 to 40 of about 1,261,152 (360)

Inclusion of optic nerve involvement in dissemination in space criteria for multiple sclerosis

open access: yesNeurology, 2018
Objective To investigate the effect of including optic nerve involvement in dissemination in space (DIS) criteria for diagnosis of multiple sclerosis (MS) in patients with clinically isolated syndrome (CIS).
W. Brownlee   +5 more
semanticscholar   +1 more source

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

open access: yesBrain Sciences, 2023
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng   +4 more
doaj   +1 more source

Predictions of Optic Nerve Traction Forces and Peripapillary Tissue Stresses Following Horizontal Eye Movements.

open access: yesInvestigative Ophthalmology and Visual Science, 2017
Purpose To use finite element (FE) analysis to predict the optic nerve sheath traction forces that act on the optic nerve head (ONH) following horizontal eye movements, and the resulting stress levels in the peripapillary connective tissues of the ONH ...
Xiaofei Wang   +4 more
semanticscholar   +1 more source

Optic Nerve Avulsion after Blunt Trauma [PDF]

open access: yes, 2014
Optic nerve avulsion is an uncommon presentation of ocular trauma with a poor prognosis. It can be seen as complete or partial form due to the form of trauma.
Güner Üney   +2 more
core   +1 more source

NRF2 Deficiency Disrupts Mitochondrial Homeostasis via NDUFS7 in Trabecular Meshwork

open access: yesResearch
The trabecular meshwork (TM) plays a pivotal role in maintaining intraocular pressure (IOP) by regulating aqueous humor outflow. Nuclear factor erythroid 2-related factor 2 (NRF2) was identified as a key transcriptional controller of TM redox balance and
Xuejing Yan   +6 more
doaj   +1 more source

Approach to the Diagnosis and Differentiation of Glaucomatous and Nonglaucomatous Optic Neuropathies [PDF]

open access: yes, 2014
Optic neuropathy denotes degeneration of the retinal ganglion cells with functional and structural impairment of the optic nerve. Functional damage of the optic nerve can be evaluated by checking visual acuity, color vision, pupillary function, and ...
Carmen K. M. Chan   +3 more
core   +1 more source

Mechanical activation of PIEZO1 drives AP-1–dependent PTGS2/PGE2 signaling and corneal inflammation

open access: yesiScience
Summary: Abnormal mechanical stimulation, such as eye rubbing, is a critical risk factor for corneal diseases, yet the molecular mechanisms linking mechanical stimulation to inflammation remain unclear.
Zongzheng Zou   +10 more
doaj   +1 more source

Low-Field Magnetic Resonance Imaging Findings in 18 Dogs With Presumed Optic Neuritis

open access: yesFrontiers in Veterinary Science, 2021
Canine optic neuritis has been attributed to a focal or disseminated form of granulomatous meningoencephalitis (GME) amongst other etiologies. Magnetic resonance imaging (MRI) has been proven to help differentiate the structures within the optic nerve ...
Laura Muñiz Moris   +2 more
doaj   +1 more source

Optic Nerve Sheath Meningioma [PDF]

open access: yes, 2020
Optic nerve sheath meningioma is a benign (not malignant) tumor which involves the covering of the optic nerve.
NANOS
core  

Characterization of adeno-associated viral transduction of retinal ganglion cells in adult and old mice

open access: yesMolecular Therapy: Methods & Clinical Development
Adeno-associated viral (AAV) vectors are being used increasingly in developing treatments for age-related ocular diseases, including those impacting retinal ganglion cells (RGCs), the output neurons of the eye.
Delaney CM. Henderson   +1 more
doaj   +1 more source

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