Results 51 to 60 of about 685,293 (263)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
The contribution of brain reorganisation to recovery in patients with optic neuritis [PDF]
, 2010 In this thesis, the mechanisms of damage and repair in clinically isolated optic neuritis (ON) were investigated in vivo, by combining magnetic resonance imaging (MRI), electrophysiology and optical coherence tomography (OCT).
Jenkins, T.M.
core
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Papilledema in Space Flight: Pathogenesis, Diagnostics and Monitoring
Oftalʹmologiâ, 2020 Some Russian cosmonauts in space flight have revealed swelling of the optic nerve head of varying severity. Four clinical cases presented in this article.
I. A. Makarov, S. N. Danilichev
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Optic nerve aplasia: A case series
Indian Journal of Ophthalmology, 2018 Optic nerve aplasia (ONA) is a congenital optic nerve anomaly characterized by the absence of optic nerve head, retinal blood vessels, retinal ganglion cells, and optic nerve fibers in a malformed eye.
K Samyukta Sadasivan +3 more
doaj +1 more source
Vasculature of the distal part of optic nerve [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. Vascularisation of the distal, namely intracranial and intracanalicular parts of the optic nerve have not been explained in conventional textbooks of anatomy, while there have been explanations of proximal, that is intraorbital segment ...
Nagulić Mirjana +5 more
doaj +1 more source
, 2021 Enhancement of the optic nerve is occasionally noted in patients with arteritic ischemic optic neuropathy (ION) and non-arteritic anterior ION. We report a rare case of bilateral optic nerve enhancement in hypotension-related posterior ION (PION)
Mehdi Tavakoli; Michael S. Vaphides +1 more
core
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source