Results 71 to 80 of about 179,043 (317)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Morphometric analysis of myelinated fibre composition in the optic nerve of adult C57BL and CBA strain mice and (C57BL x CBA) F1 hybrid:a comparison of interstrain variation

, 1995
In a study involving 50 optic nerves isolated from 3 different strains of adult male mice, C57BL, CBA and (C57BL x CBA) F1 hybrids, and from adult female CBA strain mice, we observed that the mouse had a lower mean total myelinated nerve fibre count than
Dangata, Y Y, Findlater, G S, Kaufman, M H   +2 more
core  

Endoscopic endonasal orbital and optic nerve decompression for traumatic orbital injuries: A review of outcome

, 2022
I n t r o d u c t i o n : Orbital and optic nerve decompression has evolved over the years from an open surgery initially, to the current endoscopic approach.
Lee, Eng Ssiang, Ng, Boon Han Kevin, Tang, Ing Ping   +2 more
core   +1 more source

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Traumatic optic neuropathy: Surgical intervention improves vision and color perception

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
The most common cause of traumatic optic neuropathy (TON) is indirect injury to the optic nerve, which is thought to be the result of transmitted shock from an orbital impact to the intracanalicular portion of optic nerve.
Sujit Das
doaj   +1 more source

Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons

, 2003
Transplantation of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional recovery.
Raisman, G., Li, D., Li, Y., Lund, R.D., Sauvé, Y.   +4 more
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

The contribution of brain reorganisation to recovery in patients with optic neuritis

, 2010
In this thesis, the mechanisms of damage and repair in clinically isolated optic neuritis (ON) were investigated in vivo, by combining magnetic resonance imaging (MRI), electrophysiology and optical coherence tomography (OCT).
Jenkins, T.M.
core  

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Microscopic details of age related changes in rat optic nerve

Senses and Sciences, 2014
Background: Age-related changes in the number and density of optic nerve fibres were studied in 12-month-old (adult) and 24-month-old (aged) male Wistar rats.
Fernanda Pacella, Elena Pacella, Maria Rosaria Carbotti, Giulio De Paolis, Roberto Muscella, Carlo Cavallotti   +5 more
doaj   +1 more source