Results 91 to 100 of about 1,261,152 (360)

Distribution of Mesenchymal Stem Cells and Effects on Neuronal Survival and Axon Regeneration after Optic Nerve Crush and Cell Therapy

open access: yesPLoS ONE, 2014
Bone marrow-derived cells have been used in different animal models of neurological diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) injected into the vitreous body in a model of optic nerve injury.
Louise A. Mesentier-Louro   +11 more
semanticscholar   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Emergency management: optic nerve compression [PDF]

open access: yes, 2018
Increased orbital pressure compresses the optic nerve, which can lead to irreversible vision loss in a matter of ...
Colin Cook
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Jak/Stat Signaling Stimulates Zebrafish Optic Nerve Regeneration and Overcomes the Inhibitory Actions of Socs3 and Sfpq

open access: yesJournal of Neuroscience, 2014
The regenerative failure of mammalian optic axons is partly mediated by Socs3-dependent inhibition of Jak/Stat signaling (Smith et al., 2009, 2011). Whether Jak/Stat signaling is part of the normal regenerative response observed in animals that exhibit ...
Fairouz Elsaeidi   +3 more
semanticscholar   +1 more source

Anatomy of the Human Optic Nerve: Structure and Function [PDF]

open access: yes, 2018
The optic nerve (ON) is constituted by the axons of the retinal ganglion cells (RGCs). These axons are distributed in an organized pattern from the soma of the RGC to the lateral geniculated nucleus (where most of the neurons synapse).
Triviño Casado, Alberto   +19 more
core   +1 more source

The Morphological Description Automation of the Optic Nerve Head Boundary in Digital Fundus Images

open access: yesOftalʹmologiâ, 2018
Purpose. To develop the automating method for the description of the optic nerve head condition. The method allows to differentiate the optic nerve head with clear boundaries typical for the normal fundus and optic nerve head with blurred boundaries ...
E. G. Tanaeva, R. G. Khafizov
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Three Types of Optic Disc Edema in Optic Nerve Sheath Meningioma [PDF]

open access: yes, 2021
ONSM (optic nerve sheath meningioma) accounts for approximately 2% of all orbital tumors and represents around 1-2% of all meningiomas. Classical triad of progressive visual loss, optic nerve atrophy, and presence of optociliary shunt vessels is ...
Susiani Intan; Shannon Beres; Heather Moss; Joyce Liao
core  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

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