Results 61 to 70 of about 685,293 (263)
Background Optic nerve head measurements extracted from optical coherence tomography (OCT) show promise for monitoring clinical conditions with elevated optic nerve heads.
Megh D. Patel +2 more
doaj +1 more source
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Development of a novel SupraChoroidal-to-Optic-NervE (SCONE) drug delivery system
Purpose Targeted drug delivery to the optic nerve head may be useful in the preclinical study and later clinical management of optic neuropathies, however, there are no FDA-approved drug delivery systems to achieve this.
Bryce Chiang +6 more
doaj +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
The Morphological Description Automation of the Optic Nerve Head Boundary in Digital Fundus Images
Purpose. To develop the automating method for the description of the optic nerve head condition. The method allows to differentiate the optic nerve head with clear boundaries typical for the normal fundus and optic nerve head with blurred boundaries ...
E. G. Tanaeva, R. G. Khafizov
doaj +1 more source
Three Types of Optic Disc Edema in Optic Nerve Sheath Meningioma
ONSM (optic nerve sheath meningioma) accounts for approximately 2% of all orbital tumors and represents around 1-2% of all meningiomas. Classical triad of progressive visual loss, optic nerve atrophy, and presence of optociliary shunt vessels is ...
Susiani Intan; Shannon Beres; Heather Moss; Joyce Liao
core
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Optic nerve as a source of activated retinal microglia post-injury
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons.
Neal D. Heuss +6 more
doaj +1 more source
Correlation of optic nerve and optic nerve sheath diameter with intracranial pressure in pigs. [PDF]
OBJECTIVE Several studies have shown an association between intracranial pressure and the diameter of the optic nerve sheath measured by transbulbar ultrasonography. To understand the pathophysiology of this phenomenon, we aimed to measure the changes
J. Beck (8399460) +35 more
core +2 more sources

