Results 31 to 40 of about 26,703 (203)

Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]

, 2018
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA, Brück, Wolfgang, Feldmann, Linda, Häusler, Darius, Häusser-Kinzel, Silke, Lehmann-Horn, Klaus, Lepennetier, Gildas, Torke, Sebastian, Weber, Martin S, Zamvil, Scott S   +9 more
core   +1 more source

Painful tonic spasms in a patient with neuromyelitis optica spectrum disorder: A case report

SAGE Open Medical Case Reports, 2023
Painful tonic spasms initially described in association with multiple sclerosis are actually more common in patients with neuromyelitis optica spectrum disorder.
Roshan Aryal, Sushan Homagian, Suraj Shrestha, Bikram Prasad Gajurel, Ragesh Karn, Reema Rajbhandari, Niraj Gautam, Ashish Shrestha, Sumit Shahi, Rajeev Ojha   +9 more
doaj   +1 more source

Familial neuromyelitis optica [PDF]

Neurology, 2010
Detection of aquaporin-4-specific immunoglobulin G (IgG) has expanded the spectrum of neuromyelitis optica (NMO). Rare reports of familial aggregation have suggested a component of genetic susceptibility but these reports mostly antedated the discovery of the NMO-IgG biomarker and recently updated diagnostic criteria.We report a case series describing ...
M, Matiello, H J, Kim, W, Kim, D G, Brum, A A, Barreira, D J, Kingsbury, G T, Plant, T, Adoni, B G, Weinshenker   +8 more
openaire   +2 more sources

Severe optic neuritis in a patient with combined neuromyelitis optica spectrum disease and primary Sjögren’s syndrome: a case report

Journal of Medical Case Reports, 2012
Introduction Optic neuritis, although uncommon, can be the initial presentation of Sjögren’s syndrome. Coexisting Sjögren’s syndrome has also been reported with neuromyelitis optica spectrum disorder.
Tan Petrina, Yu Wai, Umapathi Thirugnanam, Lim Su-Ann   +3 more
doaj   +1 more source

Course of neuromyelitis optica during inadvertent pregnancy in a patient treated with rituximab [PDF]

, 2009
In neuromyelitis optica (NMO), the monoclonal B-cell antibody rituximab is a therapeutic option. Little is known about the course of NMO and the safety of rituximab during pregnancy.
Hohlfeld, R., Kümpfel, Tania, Pellkofer, H. L., Schulze, A., Suessmair, C.   +4 more
core   +1 more source

Neuromyelitis Optica with NMO-IgG/ Anti-AQP4 Antibody Positive: First Case Reported from Uttarakhand India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Neuromyelitis optica (also known as Devic’s disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord.
Manish Mittal, Garima Mittal
doaj   +1 more source

Case Report: Clinical and Imaging Characteristics of a Patient with Anti-flotillin Autoantibodies: Neuromyelitis Optica or Multiple Sclerosis?

Frontiers in Immunology, 2021
BackgroundDemyelination diseases are complex puzzles that are not always straightforward to diagnose. Multiple sclerosis and neuromyelitis optica are two that are frequently encountered.
Ke Shang, Chang Cheng, Chuan Qin, Jun Xiao, Gang Deng, Bi-Tao Bu, Sha-Bei Xu, Dai-Shi Tian   +7 more
doaj   +1 more source

A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]

, 2018
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams, Adams, Akassoglou, Akassoglou, Akenami, Akenami, Albright, Alizadeh, Alonso, Amor, Antoniak, Beggs, Bidot, Bitsch, Boesen, Brkic, Bronstein, Brunetti, Castellino, Cesarman-Maus, Chapman, Chelmicka-Szorc, Claudio, Compston, Coughlin, Cuzner, Danø, Davalos, Davalos, Davidson, Davie, De Luca, Dekaban, Deschepper, Donovan, East, Ed Rainger, Engelmann, Esmon, Esmon, Fan, Fan, Farber, Feldman, Ferguson, Festoff, Field, Fiorini, Flick, Fog, Friedman, Garcia-Monco, García, Garg, Genc, Gloor, Griffin, Griffin, Guenther, Gveric, Göbel, Göbel, Göbel, Hafler, Han, Horstman, Huszak, Inaba, Inoue, Iong, Jacob, Jones, Kalaria, Kirichuk, Kirk, Kirk, Knauer, Koudriavtseva, Koudriavtseva, Koudriavtseva, Koudriavtseva, Kreutzberg, Kuhlmann, Kwon, Lane, Langer, Lassmann, Lassmann, Lassmann, Lesny, Liddelow, Lider, Lin, Lin, Lock, Lu, Mahmood, Mandoj, Marik, Mechelli, Miranda, Moll, Murray, Park, Parsons, Paterson, Perez, Persson, Persson, Petersen, Phillips, Pike, Plantone, Plumb, Putnam, Putnam, Rand, Reese, Reinhard, Roizin, Ryu, Ryu, Saberi, Savitky, Seeds, Seeds, Sheremata, Simón, Smith, Sobel, Soon, Sotnikov, Spadaro, Starossom, Starossom, Stavrou, Stolz, Teesalu, Tennent, Ugarova, Uzawa, van der Poll, Varga, Verrall, Wachowicz, Wakefield, Weisel, Whitlock, Wittinghofer, Wolter, Wright, Xue, Yadav, Yamaji, Yates, Yuksel, Zhang, Ziliotto, Zivadinov   +158 more
core   +1 more source

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias, Asseyer, Susanna, Bellmann-Strobl, Judith, Hauser, Anja E., Koppen, Sofie van, Lindquist, Randall L., Mothes, Ronja, Niesner, Raluca A., Ostendorf, Lennard, Paul, Friedemann, Radbruch, Helena, Ruprecht, Klemens   +11 more
core   +3 more sources

Relapse of Neuromyelitis Optica Spectrum Disorder Associated with Intravenous Lidocaine

Case Reports in Medicine, 2011
Lidocaine unmasks silent symptoms and eases neuropathic pain in multiple sclerosis patients; however, the effects of lidocaine in neuromyelitis optica have never been reported.
Akiyuki Uzawa, Masahiro Mori, Saeko Masuda, Kazuhiko Aoe, Satoshi Kuwabara   +4 more
doaj   +1 more source