Results 31 to 40 of about 52,154 (152)

Anaesthesia and demyelinating disease [PDF]

open access: yesAnaesthesia, 1980
Summary The demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and techniques are ...
R M, Jones, T E, Healy
openaire   +2 more sources

Iron Rim Lesions as a Specific and Prognostic Biomarker of Multiple Sclerosis: 3T-Based Susceptibility-Weighted Imaging

open access: yesDiagnostics, 2023
This study aimed to identify the clinical significance of iron rim lesions (IRLs) in distinguishing multiple sclerosis (MS) from other central nervous system (CNS) demyelinating diseases, determine the relationship between IRLs and disease severity, and ...
Sooyoung Kim   +3 more
doaj   +1 more source

Exosomal Circular RNA as a Biomarker Platform for the Early Diagnosis of Immune-Mediated Demyelinating Disease

open access: yesFrontiers in Genetics, 2019
Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He   +6 more
doaj   +1 more source

Peripheral Demyelinating Diseases: From Biology to Translational Medicine

open access: yesFrontiers in Neurology, 2019
Demyelinating diseases represent a spectrum of disorders that impose significant burden on global economy and society. Generally, the prognosis of these diseases is poor and there is no available cure.
Khidhir Kamil   +4 more
doaj   +1 more source

Cognitive Impairment Screening in Multiple Sclerosis Using CoGeval: Clinical and Functional Predictors in a Mexican Cohort

open access: yesSclerosis
Background/Objectives: Cognitive impairment is frequent in multiple sclerosis, yet routine screening is inconsistently implemented. We aimed to characterize cognitive impairment using CogEval in a Mexican cohort and to identify clinical and functional ...
Luis F. Hernández Salomón   +3 more
doaj   +1 more source

Genetics of Demyelinating Diseases

open access: yesBrain Pathology, 1996
Multiple sclerosis(MS), the prototypic demyelinating disease in humans, is the most common cause of acquired neurological dysfunction arising between early to mid adulthood. MS is an inflammatory disorder and is believed to result from an autoimmune response, directed against myelin proteins and perhaps other antigens, resulting in demyelination and ...
J R, Oksenberg, E, Seboun, S L, Hauser
openaire   +2 more sources

CAR T-Cell Immunotherapy in Neuroautoimmune Diseases: Focus on the Central Nervous System

open access: yesBiomedicines
The treatment of central nervous system (CNS) autoimmune diseases has evolved from broad immunosuppression toward targeted disease-modifying therapies (DMTs).
Fotis Demetriou, Maria Anagnostouli
doaj   +1 more source

The virology of demyelinating diseases [PDF]

open access: yesAnnals of Neurology, 1994
Infectious agents have been postulated as causes of multiple sclerosis for over a century. The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and "viral" infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections in humans can cause diseases with
openaire   +2 more sources

The Heart’s Electromagnetic Field in Emotions, Empathy and Human Connection: Biosensor-Derived Insights into Heart–Brain Axis Mechanisms and a Basis for Novel BioMagnetoTherapies

open access: yesSensors
The heart’s electromagnetic field (HEMF) represents the strongest magnetic signal in the human body and has been increasingly associated with processes related to the Heart–Brain Axis (HBA).
Andreas Palantzas, Maria Anagnostouli
doaj   +1 more source

Diffusion Weighted Imaging versus Contrast- enhanced T1-weighted Imaging Sequences in Inflammatory Demyelinating Diseases of Brain: A Cross-sectional Study

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2022
Introduction: Based on the literature, Contrast-enhanced T1- Weighted (CE T1WI) imaging sequence is considered as the gold standard radiological marker of active inflammatory demyelinating diseases of brain.
KR Manohar Kumar   +2 more
doaj   +1 more source

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