Results 31 to 40 of about 5,870 (242)

Endothelin-1 contributes to the development of virus-induced demyelinating disease

open access: yesJournal of Neuroinflammation, 2020
Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin   +4 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 1. Characteristics and physiological functions [PDF]

open access: yesFarmacja Polska, 2022
The nervous system is composed of two dominant types of cells – neurons and glial cells. They differ from each other both morphologically and physiologically.
Mateusz Maszczyk   +2 more
doaj   +1 more source

Demyelination in rheumatic diseases [PDF]

open access: yesPostgraduate Medical Journal, 2008
Abstract Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterised by multifocal areas of demyelination in the white matter of the brain and spinal cord. Autoantibodies, for example antinuclear antibodies, can also be present.
A, Theodoridou, L, Settas
openaire   +3 more sources

Genetic Basis of Inflammatory Demyelinating Diseases of the Central Nervous System: Multiple Sclerosis and Neuromyelitis Optica Spectrum

open access: yes, 2023
Demyelinating diseases alter myelin or the coating surrounding most nerve fibers in the central and peripheral nervous systems. The grouping of human central nervous system demyelinating disorders today includes multiple sclerosis (MS) and neuromyelitis ...
Blanca M. G. Torres-Mendoza   +6 more
core   +1 more source

Fulminant Demyelinating Diseases [PDF]

open access: yesThe Neurohospitalist, 2013
Fulminant demyelinating disease is a heading that covers acute disseminated encephalomyelitis and its variant acute hemorrhagic leukoencephalitis (Hurst disease), severe relapses of multiple sclerosis (MS), variants of MS (tumefactive MS, Marburg variant, Balo concentric sclerosis, myelinoclastic diffuse sclerosis), and neuromyelitis optica-spectrum ...
Megan R, Rahmlow, Orhun, Kantarci
openaire   +2 more sources

Moyamoya Disease May Mimic Multiple Sclerosis?

open access: yesCase Reports in Neurological Medicine, 2019
Introduction. A wide range of medical conditions may mimic multiple sclerosis. Among them, cerebrovascular diseases, including moyamoya disease, need to be excluded since they share common clinical features and radiographic findings with multiple ...
Ioanna Spanou   +7 more
doaj   +1 more source

Hedgehog Signaling in CNS Remyelination

open access: yesCells, 2022
Remyelination is a fundamental repair process in the central nervous system (CNS) that is triggered by demyelinating events. In demyelinating diseases, oligodendrocytes (OLs) are targeted, leading to myelin loss, axonal damage, and severe functional ...
Minxi Fang   +3 more
doaj   +1 more source

Predicting relapse in demyelinating diseases in children [PDF]

open access: yes, 2021
Introduction. Predicting relapse in acute demyelinating episode (ADE) in children is an urgent problem, since progressive demyelinating diseases are associated with the risk of disability and cognitive impairment.Введение.
Невмержицкая, К. С.   +5 more
core  

Anaesthesia and demyelinating disease [PDF]

open access: yesAnaesthesia, 1980
Summary The demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and techniques are ...
R M, Jones, T E, Healy
openaire   +2 more sources

Iron Rim Lesions as a Specific and Prognostic Biomarker of Multiple Sclerosis: 3T-Based Susceptibility-Weighted Imaging

open access: yesDiagnostics, 2023
This study aimed to identify the clinical significance of iron rim lesions (IRLs) in distinguishing multiple sclerosis (MS) from other central nervous system (CNS) demyelinating diseases, determine the relationship between IRLs and disease severity, and ...
Sooyoung Kim   +3 more
doaj   +1 more source

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