Results 41 to 50 of about 5,870 (242)

Exosomal Circular RNA as a Biomarker Platform for the Early Diagnosis of Immune-Mediated Demyelinating Disease

Frontiers in Genetics, 2019
Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He, Ming Ren, Ming Ren, Haiqi Li, Le Yang, Xiaofeng Wang, Qiwei Yang   +6 more
doaj   +1 more source

Differential diagnosis of demyelinating diseases: what's new?

Arquivos de Neuro-Psiquiatria, 2022
Background: Acquired demyelinating disorders lead to overlapping visual, pyramidal, sensory, autonomic, and cerebellar deficits and may lead to severe disability.
Ana Beatriz Ayroza Galvão Ribeiro Gomes, Tarso Adoni   +1 more
doaj   +1 more source

Cognitive Impairment Screening in Multiple Sclerosis Using CoGeval: Clinical and Functional Predictors in a Mexican Cohort

Sclerosis
Background/Objectives: Cognitive impairment is frequent in multiple sclerosis, yet routine screening is inconsistently implemented. We aimed to characterize cognitive impairment using CogEval in a Mexican cohort and to identify clinical and functional ...
Luis F. Hernández Salomón, José A. Mejía Chávez, Diana M. S. Sánchez Galván, Luis E. Zapata Mercado   +3 more
doaj   +1 more source

Genetics of Demyelinating Diseases

Brain Pathology, 1996
Multiple sclerosis(MS), the prototypic demyelinating disease in humans, is the most common cause of acquired neurological dysfunction arising between early to mid adulthood. MS is an inflammatory disorder and is believed to result from an autoimmune response, directed against myelin proteins and perhaps other antigens, resulting in demyelination and ...
J R, Oksenberg, E, Seboun, S L, Hauser
openaire   +2 more sources

Therapeutic potential of neuromodulation for demyelinating diseases

Neural Regeneration Research, 2021
Neuromodulation represents a cutting edge class of both invasive and non-invasive therapeutic methods which alter the activity of neurons. Currently, several different techniques have been developed - or are currently being investigated – to treat a wide
Elliot H Choi, Chioma Nwakalor, Nolan J Brown, Joonho Lee, Michael Y Oh, In Hong Yang   +5 more
doaj   +1 more source

Conduction in segmentally demyelinated mammalian central axons.

, 1997
The prominent symptoms associated with central demyelinating diseases such as multiple sclerosis (MS) are primarily caused by conduction deficits in affected axons.
Paul A. Felts, Baker, Theresa A., Theresa A. Baker, Felts, PA, Smith, KJ, Smith, Kenneth J., Felts, Paul A.; id_orcid, Kenneth J. Smith, Baker, TA   +8 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

The Na+/Ca2+ exchangers in demyelinating diseases

, 2020
Intracellular [Na+]i and [Ca2+]i imbalance significantly contribute to neuro-axonal dysfunctions and maladaptive myelin repair or remyelination failure in chronic inflammatory demyelinating diseases such as multiple sclerosis.
de Rosa V., Secondo A., Pannaccione A., Boscia F., Cammarota M., Annunziato L.   +5 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

CAR T-Cell Immunotherapy in Neuroautoimmune Diseases: Focus on the Central Nervous System

Biomedicines
The treatment of central nervous system (CNS) autoimmune diseases has evolved from broad immunosuppression toward targeted disease-modifying therapies (DMTs).
Fotis Demetriou, Maria Anagnostouli
doaj   +1 more source