Results 61 to 70 of about 56,601 (283)

Infectious causes of demyelinating central nervous system diseases

, 2021
U demijelinizacijske bolesti središnjeg živčanog sustava (SŽS) svrstavaju se brojne bolesti čije je glavno obilježje oštećenje mijelinske ovojnice, tj. demijelinizacija živčanih vlakana u mozgu, kralježničnoj moždini ili vidnim živcima.
Majić, Ina
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Central nervous system B-cell lymphoma in a patient diagnosed with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids: A case report

SAGE Open Medical Case Reports
This is a case presentation of a primary central nervous system B-cell lymphoma in a 69-year-old woman with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids and chronic immunosuppressive treatment. The patient
Evangelos Koumasopoulos, Evangelia-Anna Spiteri, Aigli G Vakrakou, Panagiotis Toulas, Georgios Velonakis, George Stranjalis, Leonidas Stefanis, Maria-Eleptheria Evangelopoulos, Maria Anagnostouli   +8 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Physical Trauma and Demyelinating Diseases: A Systematic Review and Meta-Analysis

High Yield Medical Reviews
Background Although several observational studies investigated the relationship between physical trauma and demyelinating diseases, the relationship is still controversial in the literature.
Ahmad Toubasi, Thuraya Al-Sayegh
doaj   +1 more source

Parkinsonism and neurosarcoidosis: Cause and effect or coincidence?

Clinical Parkinsonism & Related Disorders, 2019
Movement disorders in demyelinating diseases can be coincidental or secondary to a demyelinating lesion. We here report the first case of coincidental association of neurosarcoidosis and idiopathic Parkinson's disease.
Raja Mehanna, Lael Stone, Ilia Itin
doaj   +1 more source

Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model

Cells, 2022
Oligodendrocytes are glial cells located in the central nervous system (CNS) that play essential roles in the transmission of nerve signals and in the neuroprotection of myelinated neurons.
Pei-Lun Lai, Chi-Hou Ng, Chia-Hsin Wu, Chien-Ying Lai, Scott C. Schuyler, Vicki Wang, Hsuan Lin, Yueh-Chang Lee, Ming-Hsi Chuang, Chang-Huan Yang, Wei-Ju Chen, Hsiao-Chun Huang, Jean Lu   +12 more
doaj   +1 more source

Demyelinating Diseases 2: NMO, ADEM, GBS, CIDP (DRAFT)

, 2018
The video in this chapter explores demyelinating diseases, and focuses on neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM), Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP), including their
Tracey Milligan, Tamara Kaplan
core   +1 more source