Results 211 to 220 of about 131,881 (286)

Proximity‐Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases

open access: yesAngewandte Chemie, EarlyView.
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Lomane Berthy   +20 more
wiley   +2 more sources

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

An Antarctic toothfish eye lens protein resists thermal stress even when extensively deamidated. [PDF]

open access: yesBiophys Rep (N Y)
Sroge C   +6 more
europepmc   +1 more source

Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase. [PDF]

open access: yesJACS Au
Yehorova D   +12 more
europepmc   +1 more source

Plasma-Coated Collagen Membranes Gain Barrier Function Through Heat Treatment. [PDF]

open access: yesJ Funct Biomater
Apaza Alccayhuaman KA   +7 more
europepmc   +1 more source

Thermally Controlled Chiral Supramolecular Polymorphism in Water

open access: yesAngewandte Chemie International Edition, EarlyView.
Using an amphiphilic oligo(phenyleneethynylene) derivative, we establish LCST‐coupled chirality as a strategy to regulate thermoresponsive supramolecular polymorphism in water. At room temperature, AggI forms discrete assemblies that transform into elongated helical fibers (AggII) near the LCST and subsequently to sheet‐like structures (AggIII) at ...
Zulema Fernández   +6 more
wiley   +1 more source

Stoichiometrically Engineered Hydrated Ionic Liquids Enabling Reinforcement of Enzyme Cascade with Improved Thermodynamic Stability. [PDF]

open access: yesACS Sustain Chem Eng
Biswas S   +7 more
europepmc   +1 more source

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