Proximity‐Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Lomane Berthy +20 more
wiley +2 more sources
FitFoldData: A Web-Based Toolkit for Circular Dichroism and Differential Scanning Calorimetry Data Analysis of Protein Thermal Denaturation. [PDF]
Yeritsyan KV, Badasyan AV.
europepmc +1 more source
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo +7 more
wiley +1 more source
Cytotoxicity and DNA Damage Ability of Isomeric <i>meso</i>-Tetra(cisplatin)porphyrins in Keratinocytes and Melanoma Cells Treated with Photodynamic Therapy. [PDF]
Peranzoni NP +5 more
europepmc +1 more source
An Antarctic toothfish eye lens protein resists thermal stress even when extensively deamidated. [PDF]
Sroge C +6 more
europepmc +1 more source
Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase. [PDF]
Yehorova D +12 more
europepmc +1 more source
Plasma-Coated Collagen Membranes Gain Barrier Function Through Heat Treatment. [PDF]
Apaza Alccayhuaman KA +7 more
europepmc +1 more source
Thermally Controlled Chiral Supramolecular Polymorphism in Water
Using an amphiphilic oligo(phenyleneethynylene) derivative, we establish LCST‐coupled chirality as a strategy to regulate thermoresponsive supramolecular polymorphism in water. At room temperature, AggI forms discrete assemblies that transform into elongated helical fibers (AggII) near the LCST and subsequently to sheet‐like structures (AggIII) at ...
Zulema Fernández +6 more
wiley +1 more source
Stoichiometrically Engineered Hydrated Ionic Liquids Enabling Reinforcement of Enzyme Cascade with Improved Thermodynamic Stability. [PDF]
Biswas S +7 more
europepmc +1 more source
Effects of Freezing, Frozen Storage and Thawing on the Water Status, Quality, Nutrition and Digestibility of Meat: A Review. [PDF]
Zhu Y, Zhu J, Shi X, Fan M.
europepmc +1 more source

