Results 221 to 230 of about 78,856 (294)

The HIF‐1α Pathway Regulates Satellite Cell Fate During Aging Through Histone Lactylation

Aging Cell, Volume 25, Issue 2, February 2026.
FG‐4592–induced activation of HIF‐1α enhances anaerobic glycolysis and promotes lactate‐driven PAX7 lactylation, thereby boosting satellite cell activity and counteracting age‐related muscle decline. ABSTRACT Aging‐associated sarcopenia is driven in part by the progressive loss of type II glycolytic fibers and the functional decline of their resident ...
Marco Piccoli, Lorenzo Mornatti, Ivana Lavota, Monica Risuglia, Pasquale Creo, Elena Vizzino, Paola Rota, Adriana Tarantino, Laura Mangiavini, Giuseppe Ciconte, Paola Signorelli, Giuseppe Maria Peretti, Simone Cenci, Carlo Pappone, Luigi Anastasia, Federica Cirillo   +15 more
wiley   +1 more source

Corrective Measures of Denaturing Gradient Gel Electrophoresis Limitations

Journal of Environmental Science and Technology, 2014
openaire   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

Nicotiana benthamiana as a Source of Cowpea Mosaic Virus-Derived Particles That Specifically Package Designer RNAs. [PDF]

Plant Biotechnol J
Peyret H, Shah SN, Meshcheriakova Y, Jung JW, Saunders K, Lomonossoff GP.   +5 more
europepmc   +1 more source

N‐Truncated Superoxide Dismutase‐1 in Cerebrospinal Fluid Is Folded and Active

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Superoxide dismutase 1 (SOD1) mutations cause amyotrophic lateral sclerosis (ALS) through mechanisms involving protein misfolding and aggregation. While C‐terminal truncations of SOD1 promote neurotoxicity, our study reveals that approximately one‐third of SOD1 in cerebrospinal fluid (CSF) is N‐terminally truncated—a striking observation given the ...
Laura Leykam, Karin M. E. Forsberg, Peter M. Andersen, Thomas Brännström, Sophia Weiner, John Rönnholm, Kaj Blennow, Henrik Zetterberg, Stefan L. Marklund, Johan Gobom, Per Zetterström   +10 more
wiley   +1 more source

Verification of N-Linked Glycosylation of Proteins Isolated from Plant or Mammalian Cell Lines Using PNGase Enzyme. [PDF]

Bio Protoc
Hong W, Lei C, Qiu Y, Zhou Y, Hu Y, Chen X, Li X, Li J.   +7 more
europepmc   +1 more source

16S rRNA gene-based identification of bacteria in postoperative endophthalmitis by PCR-Denaturing Gradient Gel Electrophoresis (PCR-DGGE) fingerprinting. [PDF]

Braz J Microbiol, 2012
Navarro-Noya Y, Hernández-Rodríguez C, Zenteno JC, Buentello-Volante B, Cancino-Díaz ME, Jan-Roblero J, Cancino-Díaz JC.   +6 more
europepmc   +1 more source

Purification of SlREC2 from wild-type tomato leaflets using immunoaffinity chromatography and immunoprecipitation. [PDF]

Front Plant Sci
Zhu L, Larkin RM.
europepmc   +1 more source

Synthesis of long and functionally active RNAs facilitated by acetal levulinic ester chemistry. [PDF]

Nucleic Acids Res
Lyu Z, Katolik A, Yaseen I, Pater AA, Robert F, Huang S, Gagnon KT, Unrau PJ, Damha MJ.   +8 more
europepmc   +1 more source