Results 71 to 80 of about 3,456,325 (296)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Effectively Regulating More Robust Amorphous Li Clusters for Ultrastable Dendrite‐Free Cycling

Advanced Science, 2021
A disordered phase in Li‐deposit nanostructure is greatly attractive, but plagued by the uncontrollable and unstable growth, and the nanoscale characterization in the structure.
Shizhi Huang, Junfeng Yang, Luxiang Ma, Jingyi Ding, Xusheng Wang, Chengyuan Peng, Binglu Zhao, Mengxiong Cao, Junrong Zheng, Xin‐Xiang Zhang, Jitao Chen   +10 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Designing sodium alloys for dendrite‐free sodium‐metal batteries

Information & Functional Materials
Sodium metal, with a high theoretical specific capacity (∼1165 mA h g−1) and a low redox potential (−2.71 V vs. SHE) as well as low cost, becomes an attractive option for high‐energy‐density sodium secondary batteries.
Kaitong Yao, Shitan Xu, Yang Yang, Yun Zheng, Karma Zuraqi, Dan Yang, Jue Liu, Ulaganathan Mani, Xianhong Rui   +8 more
doaj   +1 more source

Antimony-modified porous lamellar zinc as reversible and stable anode for high-performance alkaline aqueous zinc–air battery

Science and Technology of Advanced Materials
Monometallic Zn is a promising anode material for post-lithium batteries owing to its high theoretical capacity, low cost and natural abundance. However, the practical application in zinc–air batteries (ZABs) remain limited by uncontrollable dendrite ...
Muhammad Afiq Irfan Mohd Shumiri, Hikari Sakaebe, Abdillah Sani Mohd Najib, Nor Akmal Fadil   +3 more
doaj   +1 more source

Regulation of dendritic filopodial interactions by ZO-1 and implications for dendrite morphogenesis. [PDF]

PLoS ONE, 2013
Neuronal dendrites dynamically protrude many fine filopodia in the early stages of neuronal development and gradually establish complex structures. The importance of the dendritic filopodia in the formation of axo-dendritic connections is established ...
Ryouhei Komaki, Hideru Togashi, Yoshimi Takai   +2 more
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Sustained single-textured zinc electrodeposition via organic–inorganic hybrid molecular design for high-capacity aqueous zinc-metal batteries

Nano Research
The uncontrolled zinc electrodeposition in aqueous electrolytes, characterized by crystallographic randomness, remains a fundamental challenge due to dendritic growth and parasitic reactions.
Haoran Du, Shanjie Zhang, Wenjuan Yang, Kunhong Hu, Lei Hu, Xinfeng Zhang, Yi Zhao, Wei Yang, Xin Liang, Long Qie   +9 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source