Results 61 to 70 of about 2,025,180 (241)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Dendrite architecture determines mitochondrial distribution patterns in vivo.

Cell Reports
Neuronal morphology influences synaptic connectivity and neuronal signal processing. However, it remains unclear how neuronal shape affects steady-state distributions of organelles like mitochondria.
Eavan J. Donovan, Anamika Agrawal, Nicole Liberman, Jordan I. Kalai, Avi J. Adler, Adam M Lamper, Hailey Q. Wang, Nicholas J. Chua, Elena F. Koslover, E. L. Barnhart   +9 more
semanticscholar   +1 more source

Influence of Game-Based Learning in Mathematics Education on Students’ Affective Domain: A Systematic Review

Mathematics, 2021
In modern education nowadays, the use of game-based learning as a teaching and learning method is popular in all school subjects, including mathematics.
P. Vankúš
semanticscholar   +1 more source

Revolutionizing Lithium Metal Anodes With 3D‐Printed Topology‐Optimized Hosts for Enhanced Stability

Advanced Science, EarlyView.
This study presents a topology‐optimized lithium metal anode host fabricated via digital light processing (DLP) 3D printing. The reinforced microstructure provides mechanical stability, suppresses dendrite growth, and accommodates volume changes.
Xin Hu, Yimin Chen, Yun‐Fei Fu, Daoguang Bi, Baozhi Yu, Ying (Ian) Chen   +5 more
wiley   +1 more source

Effects on dendritically located H‐current on synaptic integration: a mathematical model

The FASEB Journal, 2008
The h‐current (I h ) is a cation current that improves cell excitability in three interrelated ways: it helps to determine the resting potential and firing frequency; it reduces the amplitude and duration of hyperpolarizing inputs; and it generates rhythmic cell activity when coupled to other
Francisco Mariano Arencibia‐Albite, Mariano Marcano, Carlos Jimenéz‐Rivera   +2 more
openaire   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Slowing Down Zinc Electrodeposition Kinetics Can Maximize and Compromise Anode Stability: How Slow Is Too Slow?

Angewandte Chemie, EarlyView.
Zinc anode performance is maximized within an optimal deposition‐kinetic window. Additives that tune the deposition exchange current density (i0,Dep) suppress HER at intermediate values, but overly fast kinetics promote dendrites and overly slow kinetics accelerate corrosion/HER.
Md. Arif Faisal, Taizhe Liu, Ashutosh Rana, James H. Nguyen, Saptarshi Paul, Ashutosh Bhadouria, Brian M. Tackett, Jeffrey E. Dick   +7 more
wiley   +2 more sources

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Dendrites, Topological Graphs, and 2-Dominance [PDF]

, 2009
For each positive ordinal α, the reflexive and transitive binary relation of α-dominance between compacta was first defined in our paper [Mapping properties of co-existentially closed continua, Houston J.
Bankston, Paul
core   +1 more source