Results 51 to 60 of about 5,425,138 (280)

An in situ visualization system using synchrotron white X-rays to investigate the solidification behaviors of metallic materials

Journal of Synchrotron Radiation
An advanced imaging platform has been developed to study the microstructural solidification behaviors of metals using synchrotron white X-rays. This system provides submicrometre effective pixel size and a frame rate of thousands per second, enabling ...
Hyeong Uk Mo, Min Woo Kim, Chang Hun Lee, Jina Kim, Hyun Wook Park, Jae-Hong Lim, Chang Hee Yim, Cheol Hee Nam, Jong Hyun Kim, Ho Jae Kwak   +9 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Effect of Periodically Changing Regimes on the Electrodeposition of Silver Powder

International Journal of Electrochemical Science, 2011
The effect of different deposition regimes (constant and reversing currents, constant and pulsating overpotential), on the powdered and dendritic silver electrodeposits morphology were investigated.
Lj.J. Pavlović, M.G. Pavlović, M.M. Pavlović, N.D. Nikolić, M.V. Tomić   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Melt flow-induced mechanical deformation of dendrites in alloy solidification: A coupled thermal fluid - solid mechanics approach

Journal of Materials Research and Technology, 2023
Melt flow during alloy solidification promotes more dendrite fragments or equiaxed grains due to dendrite fragmentation, while the complex interactions between melt flow and dendritic growth causing flow-induced dendrite deformation and dendrite ...
Luwei Yang, Neng Ren, Chinnapat Panwisawas, Jun Li, Mingxu Xia, Hongbiao Dong, Jianguo Li   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Anisotropic Permeability in Solidifying Mushy Zones: Coupling Dendritic Kinetics to Interdendritic Transport for Predicting Solidification Defects in Metallic Alloys

Metals
The anisotropic permeability tensor governs interdendritic fluid flow and solute transport during the directional solidification of metallic alloys, fundamentally influencing crystal growth kinetics and microstructural evolution.
Bao Yang, Xiaoyong Tang, Wenming Xiong, Zhuang Li, Minglin Wang, Hui Zhang   +5 more
doaj   +1 more source

The dendritic density field of a cortical pyramidal cell [PDF]

, 2012
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail.
Hermann Cuntz, Cuntz, H. ; https://orcid.org/, Cuntz, Hermann, Hermann eCuntz   +3 more
core   +1 more source