Results 61 to 70 of about 5,425,138 (280)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Observation of Electroplating in a Lithium-Metal Battery Model Using Magnetic Resonance Microscopy

Molecules
Accurate imaging methods are important for understanding electrodeposition phenomena in metal batteries. Among the suitable imaging methods for this task is magnetic resonance imaging (MRI), which is a very powerful radiological diagnostic method.
Rok Peklar, Urša Mikac, Igor Serša
doaj   +1 more source

Modeling of microstructure formation with gas porosity growth during columnar dendritic solidification of aluminum alloys

Journal of Materials Research and Technology, 2022
In this paper, microstructure formation with gas bubble growth during columnar dendritic solidification has been numerically investigated by using the coupled lattice Boltzmann-cellular automaton-finite difference (LB-CA-FD) model, which combines the ...
Wenjian Lu, Hui Xing, Qingyu Zhang, Zefan Shen, Qi An   +4 more
doaj   +1 more source

Boundary-layer approaches to dendritic growth

Physical Review A, 1987
We analyze the derivation of boundary-layer models for dendritic growth and investigate the extent to which they yield information about the existence of a continuous family of steady-state needle crystal solutions. Although recent work has established that there exists only a discrete set of solutions for viscous fingering in a Hele-Shaw cell, side ...
Weeks, J.D., Saarloos, W. van
openaire   +5 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice [PDF]

, 2010
The pathology of Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) peptide, hyperphosphorylated tau protein, neuronal death, and synaptic loss.
Fuhrmann Martin, Kretzschmar Hans, Ochs, Simon M., Herms Jochen, Simon M Ochs, Burgold Steffen, Jochen Herms, Frank M LaFerla, Burgold, Steffen, Herms, Jochen, Hans Kretzschmar, Gerda Mitteregger, Fuhrmann, Martin, Kretzschmar, Hans, Ochs Simon M., Frank M. Laferla, LaFerla Frank M., Hoffmann, Nadine, LaFerla, Frank M., Bittner, Tobias, Bittner Tobias, Mitteregger, Gerda, Nadine Hoffmann, Simon M. Ochs, Martin Fuhrmann, Tobias Bittner, Hoffmann Nadine, Steffen Burgold, Mitteregger Gerda   +28 more
core   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Transcriptional responses of cultured rat sympathetic neurons during BMP-7-induced dendritic growth. [PDF]

PLoS ONE, 2011
Dendrites are the primary site of synapse formation in the vertebrate nervous system; however, relatively little is known about the molecular mechanisms that regulate the initial formation of primary dendrites.
Michelle M Garred, Michael M Wang, Xin Guo, Christina A Harrington, Pamela J Lein   +4 more
doaj   +1 more source

Involvement of SARA in Axon and Dendrite Growth

PLOS ONE, 2015
La Sara (Smad Anchor for Receptor Activation) joue un rôle crucial dans l'endocytose médiée par Rab5 dans les lignées cellulaires se localisant aux endosomes précoces où elle régule la morphologie et la fonction. Ici, nous avons analysé le rôle de la SARA au cours du développement neuronal et testé si elle fonctionne comme un régulateur du trafic ...
Cristina Arias, Sebastián Omar Siri, Cecı́lia Conde   +2 more
openaire   +5 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source