Results 71 to 80 of about 924,020 (209)

Mitochondrial Transplantation Preserves Regenerative Capacity of Denervated Skeletal Muscle by Disrupting a Ca2+ Overload‐Mitophagy‐Ferroptosis Circuit

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Denervation‐induced muscle atrophy progresses during the interval between nerve injury and reinnervation, and depletion of muscle satellite cells (MuSCs) contributes to impaired functional recovery. Although mitochondrial dysfunction and impaired quality control are implicated in muscle wasting, whether excessive mitochondrial ...
Haiqi Ding   +14 more
wiley   +1 more source

Changes in resting membrane potential and contractility of innervated and denervated skeletal muscle free grafts in the rat [PDF]

open access: yes, 1973
In free orthotopic auto-grafts of the extensor digitorum muscle of rats a marked temporary decrease of resting membrane potential (RMP) of two superficial layers of muscle fibres is observed at 2 days with subsequent recovery 4 days after transplantation.
Vyskočil, F.   +2 more
core   +1 more source

The dead still teach the living: Body donor dissection in the digital age of anatomy education

open access: yesAnatomical Sciences Education, Volume 19, Issue 11, Page 2008-2017, November 2026.
Abstract Donor‐based dissection has become increasingly contested in modern medical curricula as digital anatomy platforms, simulation technologies, virtual dissection tables, three‐dimensional reconstructions, and artificial intelligence‐supported learning have expanded.
Uğur Baran Kasırga
wiley   +1 more source

Dietary Polyphenols as Regulators of Protein Deposition and Muscle Health: Mechanisms, Interactions, and Functional Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 11, November 2026.
Dietary polyphenols contribute to the regulation of protein deposition and muscle health through multiple interconnected mechanisms. They promote protein synthesis and myogenic differentiation mainly by modulating the PI3K/AKT/mTOR signaling pathway and myogenic regulatory factors, while suppressing excessive protein degradation through regulation of ...
Chen Liu   +6 more
wiley   +1 more source

Effect of PQQ on energy metabolism in denervated gastrocnemius muscle.

open access: yes, 2015
On the 21st day after denervation, the gastrocnemius muscle was excised to determine basal OCR (A), ECAR (B), and the OCR to ECAR ratio (C). (D) The OCR and ECAR values of Den and Dep were plotted to show the difference in the metabolic profile between ...
Geng-Chang Yeh (835013)   +4 more
core   +1 more source

Functional electrical stimulation on paraplegic patients

open access: yesEuropean Journal of Translational Myology, 2014
We report on clinical and physiological effects of 8 months Functional Electrical Stimulation (FES) of quadriceps femoris muscle on 16 paraplegic patients. Each patient had muscle biopsies, CT-muscle diameter measurements, knee extension strength testing
Helmut Kern
doaj   +3 more sources

Muscle pathology in lower motor neuron paraplegia and h-b FES

open access: yesEuropean Journal of Translational Myology, 2010
After complete Spinal Cord Injury (SCI), causing complete disconnection between the muscle fibers and the nervous system, the denervated muscles become unexcitable with commercial electrical stimulators within several months and undergo severe atrophy ...
Ugo Carraro, Helmut Kern
doaj   +1 more source

Identification and characterization of differentially expressed genes in denervated muscle

open access: yes, 2000
Denervation results in a series of changes in skeletal muscle. To elucidate the molecular basis underlying these changes, it is important to identify the profile of altered gene expression in skeletal muscle following nerve injury.
Ip, Nancy Y.   +3 more
core   +1 more source

PPM1B and P-IKKβ expression levels correlated inversely with rat gastrocnemius atrophy after denervation

open access: yesBrazilian Journal of Medical and Biological Research, 2012
Activated inhibitor of nuclear factor-κB kinase β (IKKβ) is necessary and sufficient for denervated skeletal muscle atrophy. Although several studies have shown that Mg2+/Mn2+-dependent protein phosphatase 1B (PPM1B) inactivated IKKβ, few studies have ...
Jian Wei, Bing-Sheng Liang
doaj  

Galectin-1 expression in innervated and denervated skeletal muscle

open access: yes, 2009
Galectin-1 is a soluble carbohydrate-binding protein with a particularly high expression in skeletal muscle. Galectin-1 has been implicated in skeletal muscle development and in adult muscle regeneration, but also in the degeneration of neuronal ...
Svensson, Anna,, Tågerud, Sven,
core   +1 more source

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