Results 121 to 130 of about 61,364 (309)

Indirect Striatal Projection Neurons Drive a D2 Receptor‐Dependent Pathway to Dyskinesia and Dystonia

open access: yesMovement Disorders, EarlyView.
D2 receptor ablation in indirect‐pathway striatal neurons reduces or abolishes dyskinetic and dystonic behaviors induced by L‐DOPA or D2 receptor agonists, respectively. Contralateral turning is reduced, while forward locomotion is increased. These effects are associated with modulation of neuronal activity in dorsal striatum and external globus ...
Laura Andreoli   +5 more
wiley   +1 more source

Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle

open access: yes, 2007
International audienceChronic muscle disuse induced by denervation reduces mitochondrial content and produces muscle atrophy. To investigate the molecular mechanisms responsible for these adaptations, we assessed 1) mitochondrial biogenesis- and ...
Adhihetty, Peter J.   +4 more
core   +1 more source

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard   +9 more
wiley   +1 more source

Heart rate variability while assessing transplanted heart reinnervation

open access: yesИнновационная медицина Кубани, 2019
Key difference of the transplanted heart is its full surgical denervation which causes features of transplanted heart physiology. Eventually a great number of studies appeared and they showed signs of innervation partial restoration and its influence on ...
M. Kh. Lepshokova, E. D. Kosmacheva
doaj  

The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice

open access: yes, 2005
Background: Although previous studies have shown that the hepatic sympathetic nerve controls various physiological functions in the liver, the role of this nerve in liver injury has yet to be clarified.Aims: The purpose of this study was to elucidate the
Chida, Y, Takaki, A, Kubo, C, Sudo, N
core  

Renal Sympathetic Denervation

open access: yes, 2016
This section provides a comprehensive procedural report for renal sympathetic denervation procedure with up-to-date explanatory notes, synopsis of the indications and contraindications and potential complications in an organized and practical ...
Sebaaly, Mikhael Georges   +1 more
core   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer   +15 more
wiley   +1 more source

Reflections on Renal Denervation

open access: yesJournal of the American College of Cardiology, 2014
![Figure][1] Based upon earlier experience with surgical sympathectomy and considerable data in experimental animals, clinical studies began to evaluate whether transcatheter renal sympathetic denervation (RDN) by radiofrequency ablation could provide effective therapy for ...
openaire   +2 more sources

Renal denervation: back to reality, finally!

open access: yes, 2015
Renal denervation: back to reality ...
BRUNO, ROSA MARIA, TADDEI, STEFANO
core   +1 more source

Spatiotemporal Progression Patterns of Striatal Dopamine Depletion and Cerebral Hypoperfusion in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background The identification of Parkinson's disease (PD) subtypes is crucial for predicting the disease course and designing personalized therapeutic strategies. Objectives The aim of the study was to characterize the heterogeneity of the spatiotemporal evolutionary patterns of striatal dopamine depletion and cerebral hypoperfusion in PD ...
Yeeun Sun   +9 more
wiley   +1 more source

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