Results 61 to 70 of about 61,364 (309)

Inorganic Arsenic Exposure Decreases Muscle Mass and Enhances Denervation-Induced Muscle Atrophy in Mice

Molecules, 2020
Arsenic is a toxic metalloid. Infants with a low birth-weight have been observed in areas with high-level arsenic in drinking water ranging from 463 to 1025 μg/L.
Chang-Mu Chen, Min-Ni Chung, Chen-Yuan Chiu, Shing-Hwa Liu, Kuo-Cheng Lan   +4 more
doaj   +1 more source

A Millimeter‐Scale Implantable Magneto–Mechano–Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves

Advanced Science, EarlyView.
We report a fully wireless, circuit‐free neural stimulator built on a millimetric magneto‐mechano‐electric (MME) cantilever transducer (3 × 10 × 5 mm) with a barium titanate (BTO) piezoelectric ceramic core. Under low‐frequency alternating magnetic fields, the MME cantilever mechanically oscillates, inducing stress on the BTO element and thereby ...
Yijing Wang, Jingyu Tian, Zhe Xu, Cuiling Zhang, Jingen Wu, Ming Liu, Zhilu Ye, Xiaohui Zhang   +7 more
wiley   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Electrically Conductive and Topographically Engineered PLCL Nerve Guidance Conduits for Facial Nerve Regeneration

Advanced Electronic Materials, EarlyView.
A bio‐integrated nerve guidance conduit is developed for facial nerve regeneration by combining electrospun aligned PLCL nanofibers with a conductive tannic acid/polypyrrole‐based hydrogel coating. This optimized scaffold provides synergistic topographical cues and supports electrical stimulation, promoting enhanced neuronal differentiation and ...
Su Jeong Park, Jongmin Lee, Seonae Jang, Jin Yoo, Hyunjoon Kong, Dong‐hwee Kim, Young Sang Cho, Youngmee Jung   +7 more
wiley   +1 more source

Biomarkers of Sarcopenia: Current Status and Future Perspectives

AGING MEDICINE, EarlyView.
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo, Wenhan Li, Yi Zhang, Mengchen Liu, Kemeng Zhang, Sui Huang, Ping He   +6 more
wiley   +1 more source

Atrial fibrillation after heart transplantation

Трансплантология (Москва), 2018
Arrhythmias in heart transplant recipients remain an important but under-studied issue in transplant medicine. One of the most common arrhythmias, atrial fibrillation can cause cardioembolic complications in transplant recipients, in the same way as in ...
M. Kh. Lepshokova, E. D. Kosmachova, V. A. Porkhanov   +2 more
doaj   +1 more source

Lactate administration does not affect denervation‐induced loss of mitochondrial content and muscle mass in mice

FEBS Open Bio, 2021
Lactate is considered to be a signaling molecule that induces mitochondrial adaptation and muscle hypertrophy. The purpose of this study was to examine whether lactate administration attenuates denervation‐induced loss of mitochondrial content and muscle
Kenya Takahashi, Yu Kitaoka, Yutaka Matsunaga, Hideo Hatta   +3 more
doaj   +1 more source

Investigation into a new denervation model of the sciatic nerve zones in rats: Selective motor or sensorial denervation

Objective: This study aimed to introduce a reliable and useful model of selective sensorial or motor denervations of the sciatic nerve in rats with clinical and laboratory outcomes. Methods: The surgical technique was determined via detailed cadaveric
Fuat Uslusoy, Mustafa Asım Aydın, Levent Sarikcioglu, Hasan Rifat Koyuncuoğlu, İbrahim Metin Çiriş, Osman Gurdal, Selman Hakkı Altuntaş   +6 more
core   +1 more source

Effect of Laser Posterior Nasal Neurolysis for the Treatment of Chronic Rhinitis: A Randomized Controlled Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background To determine the safety and efficacy of laser ablation of the posterior nasal nerve (PNN) for the treatment of chronic rhinitis. Methods This study was a single‐center, prospective, single‐blinded, randomized sham‐controlled trial. Patients with a 24‐h reflective Total Nasal Symptom Score (rTNSS) ≧ 5, rhinorrhea ≧ 2, and congestion ≧
Jyun‐Yi Liao, En‐Ying Wang, Ying‐Shuo Hsu, Ming‐Shao Tsai, Cheng‐Jung Wu, Chia‐Hao Chang, Yi‐Li Hwang, Han‐Lo Teng, Jun‐Wei Hsieh, Chien‐Yu Huang   +9 more
wiley   +1 more source

Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

Cells, 2020
The decline in muscle mass and function with age is partly caused by a loss of muscle fibres through denervation. The purpose of this study was to investigate the potential of exercise to influence molecular targets involved in neuromuscular junction ...
Casper Soendenbroe, Cecilie J. L. Bechshøft, Mette F. Heisterberg, Simon M. Jensen, Emma Bomme, Peter Schjerling, Anders Karlsen, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey   +9 more
doaj   +1 more source