Results 121 to 130 of about 434,252 (248)

Dengue Virus Pathogenesis: Innate Immune Signaling and Cell Death Receptor Pathways

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
ABSTRACT Background The infection caused by the dengue virus (DENV) involves a complicated interaction between viral replication and the body's immune responses. As the first line of defense, the innate immune response limits viral replication but can also lead to immunopathology if it is improperly regulated.
Farjana Islam
wiley   +1 more source

Synthesis, Cytotoxic Activity, mRNA Expression, Total Oxidant and Antioxidant Status, and Molecular Modeling Studies of Novel Schiff Base–Thiosemicarbazone Hybrids

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
In this study, new Schiff base‐derived compounds were synthesized, and their structures were confirmed by FT‐IR, 1H‐NMR, 13C‐NMR, and HRMS analyses. The cytotoxic effects of the compounds on a prostate cancer cell line (PC3) were investigated, and it was determined that the compounds NZ10, NZ9, NZ7, and NZ4, in particular, exhibited potent anticancer ...
Anber M Anber   +10 more
wiley   +1 more source

Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop‐Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 21, November 2026.
A novel colorimetric LAMP assay targeting the org‐hp gene was developed for rapid Leptospira detection. The assay is performed in a simple water bath at 65°C for 90 min, and results can be interpreted by a color change visible to the naked eye. This method provides a sensitive, specific, and field‐adaptable diagnostic tool for use in resource‐limited ...
Peyman Ghoraishizadeh   +9 more
wiley   +1 more source

Introduction and Spread of West Nile Virus in Lazio, Italy, 2025: Molecular Epidemiology and Genomic Characterization

open access: yesJournal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT West Nile virus (WNV) is a flavivirus whose cycle involves mosquitoes and avian hosts that occasionally may infect horses and humans as “dead‐end hosts.” Human infection is mostly asymptomatic, sometimes leading to febrile or neuroinvasive disease.
Martina Rueca   +22 more
wiley   +1 more source

Quantifying the Unseen Dengue Burden: A Municipality‐Level Ascertainment Surface for Pará State, Brazilian Amazon

open access: yesJournal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT Passive dengue surveillance systematically underestimates true disease burden, and this under‐ascertainment is spatially structured rather than random. In the Brazilian Amazon, municipalities with the weakest notification infrastructure tend to coincide with those presenting the most favorable environmental conditions for vector proliferation.
Adriano Madureira dos Santos   +4 more
wiley   +1 more source

Therapeutic and Prophylactic Agents for Viral Diseases: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This review summarizes current therapeutic and prophylactic strategies for global viral diseases, including vaccines, PrEP, direct‐acting antivirals, and emerging modalities such as CRISPR and siRNA. It highlights their clinical impact, ongoing challenges, and future priorities toward broader protection, improved delivery, and more effective antiviral ...
Sawar Khan   +12 more
wiley   +1 more source

Metabolic Screening and In Silico Investigation of Eucalyptus globulus Essential Oil Bioactives Against DENV‐2 Envelope Protein

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Network pharmacology and molecular docking identify bioactive compounds from Eucalyptus globulus essential oil with potential activity against dengue virus, highlighting 70 shared targets and DENV‐2‐associated pathways. Globulol and eucalyptol show strong binding to DENV‐2 receptors, with favorable drug‐likeness and toxicity profiles, supporting their ...
Arslan Afzal   +8 more
wiley   +1 more source

Outcome of Dengue Fever in Adults

open access: yesGomal Journal of Medical Sciences, 2010
Background: Dengue fever is a mosquito borne viral infection. Recent years have seen epidemics of this disease. It manifests in three ways, a mild atypical form, classic dengue and dengue haemorrhagic fever. This study was carried out to know the outcome
Muhammad Usman   +3 more
doaj  

Regional and Temporal Dynamics of Dengue in Mexico (2020–2024): A Comprehensive Epidemiological Analysis

open access: yesReviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Dengue remains a major public health concern in Mexico, with incidence and clinical burden increasing substantially in recent years. Using national surveillance data from 2020 to 2024, this study provides a comprehensive overview of the changing epidemiological landscape, with an emphasis on geographic distribution, temporal trends, serotype ...
Blanca Taboada   +3 more
wiley   +1 more source

Mapping the Evidence for Oropouche Virus to Inform Research Prioritisation

open access: yesReviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Oropouche virus (OROV) infection has gained increasing public health attention due to the ongoing outbreaks in South and Central America. The World Health Organisation (WHO) lists OROV as a priority pathogen for epidemic and pandemic preparedness.
Sowsan F. Atabani   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy