Results 31 to 40 of about 17,083 (211)

Dengue hemorrhagic fever: a growing global menace

Journal of Water and Health, 2023
Dengue virus is an arthropod-borne virus, transmitted by Aedes aegypti among humans. In this review, we discussed the epidemiology of dengue hemorrhagic fever (DHF) as well as the disease's natural history, cycles of transmission, clinical diagnosis ...
Shakeela Parveen, Zainab Riaz, Saba Saeed, Urwah Ishaque, Mehwish Sultana, Zunaira Faiz, Zainab Shafqat, Saman Shabbir, Sana Ashraf, Amna Marium   +9 more
doaj   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1

Scientific Reports
Dengue is a mosquito-borne disease caused by dengue virus (DENV) infection, which remains a major public health concern worldwide owing to the lack of specific treatments or antiviral drugs available.
Nuttapong Kaewjiw, Thanawat Thaingtamtanha, Damini Mehra, Wanida Chawnawa, Tanapan Prommool, Chunya Puttikhunt, Adisak Songjaeng, Kessiri Kongmanas, Panisadee Avirutnan, Prasit Luangaram, Chatchawan Srisawat, Sittiruk Roytrakul, Stephan A. Bäurle, Sansanee Noisakran   +13 more
doaj   +1 more source

A epidemia de dengue/dengue hemorrágico no município do Rio de Janeiro, 2001/2002 The epidemic of dengue and hemorrhagic dengue fever in the city of Rio de Janeiro, 2001/2002

Revista da Sociedade Brasileira de Medicina Tropical, 2004
O objetivo deste estudo foi avaliar a ocorrência dos principais sinais e sintomas dos casos de dengue clássico e dengue hemorrágico na epidemia de 2001-2002 do município do Rio de Janeiro.
Clarisse Guimarães Casali, Marcelo Ricardo Reis Pereira, Luciana Maria Jabor Garcia Santos, Maíla Naves Pereira Passos, Bruno de Paula Menezes Drumond Fortes, Luis Iván Ortiz Valencia, Aline de Jesus Alexandre, Roberto de Andrade Medronho   +7 more
doaj   +1 more source

Do Hematocrit Levels Differentiate between Complicated and Uncomplicated Dengue Fever?

Pakistan Armed Forces Medical Journal, 2023
Objective: To compare mean hematocrit levels in patients with uncomplicated and complicated Dengue Fever and evaluate the role of hematocrit in differentiating uncomplicated and complicated Dengue Fever. Study Designs: Prospective longitudinal study.
Muhammad Furrukh, Saeed Bin Ayaz, Fatima Ayaz, Fawad Rahman, Saima Ambreen, Fazal Ur Rahman   +5 more
doaj   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Risk Factors that Affect The Incidence of Dengue Haemorrhagic Fever in The Work Area of Puskesmas Pare

Jurnal Kesehatan Lingkungan, 2018
Pare Community Health Center or Puskesmas is one of Puskesmas in Kecamatan Pare which has the highest number of Dengue Hemorrhagic Fever incidence that is 64 incidence in 2016.
Ericha Fitria Widyatama
doaj   +1 more source

“Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti‐Dengue Virus Activity”

ChemistryOpen, EarlyView.
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados, Manuel Alejandro Hernández‐Serda, Omar Joel Villegas‐Solís, Víctor Hugo Vázquez‐Valadez, Aldo Yoshio Alarcón‐López, Pablo A. Martínez‐Soriano, Jaqueline Ramos‐Sánchez, Tannya Karen Castro‐Jiménez, José Bustos‐Arriaga, Enrique Angeles   +9 more
wiley   +1 more source

Dengue and Dengue Hemorrhagic Fever, Brazil, 1981–2002

Emerging Infectious Diseases, 2005
In the last 5 years, Brazil has accounted for approximately 70% of reported dengue fever cases in the Americas. We analyzed trends of dengue and dengue hemorrhagic fever (DHF) from the early 1980s to 2002 by using surveillance data from the Brazilian Ministry of Health.
Douglas L. Hatch, Celina Maria Turchi Martelli, Giovanini E. Coelho, João Bosco Siqueira, Ana Cristina da Rocha Simplício   +4 more
openaire   +4 more sources

Endothelial cells in dengue hemorrhagic fever [PDF]

Antiviral Research, 2014
Therapies to prevent or reverse endothelial dysfunction and vascular leak found in dengue hemorrhagic fever (DHF) have not been identified. In this review we summarize dengue viruses and the spectrum of human disease and highlight evidence of endothelial cell dysfunction in DHF based on studies in patients and mouse and tissue culture models.
Anon Srikiatkhachorn, James F. Kelley
openaire   +3 more sources