Results 61 to 70 of about 453,666 (219)
Dengue Virus Pathogenesis: Innate Immune Signaling and Cell Death Receptor Pathways
ABSTRACT Background The infection caused by the dengue virus (DENV) involves a complicated interaction between viral replication and the body's immune responses. As the first line of defense, the innate immune response limits viral replication but can also lead to immunopathology if it is improperly regulated.
Farjana Islam
wiley +1 more source
PATHOGENESIS OF HEMORRHAGIC DUE TO DENGUE VIRUS
Dengue is a viral disease that is mediated by a mosquito, which causes morbidity and mortality. Viruses can increase vascular permeability which can lead to hemorrhagic diathesis or disseminated intravascular coagulation (DIC) known as dengue hemorrhagic
Arief Suseno, Nasronudin Nasronudin
doaj +1 more source
Background: Dengue Hemorrhagic Fever (DHF) is an acute febrile disease found in the tropics with a geographic distribution like malaria. Dengue fever is spread to humans by the Aedes aegypti mosquito. More than 100 tropical and subtropical countries have
Zulfikar Zulfikar +8 more
doaj +1 more source
This review summarizes current therapeutic and prophylactic strategies for global viral diseases, including vaccines, PrEP, direct‐acting antivirals, and emerging modalities such as CRISPR and siRNA. It highlights their clinical impact, ongoing challenges, and future priorities toward broader protection, improved delivery, and more effective antiviral ...
Sawar Khan +12 more
wiley +1 more source
Background Series of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue ...
Grace Angeline Malarnangai Kularatnam +5 more
doaj +1 more source
There is a limited supply of COVID-19 vaccines, with less than 20% of eligible populations in low-income countries having received one dose. Intradermal delivery of fractional dose vaccines is one way to improve global vaccine access, but no studies have
Somruedee Chatsiricharoenkul +17 more
doaj +1 more source
Imported Dengue Hemorrhagic Fever, Europe [PDF]
To the Editor: Dengue infection is an endemic and epidemic urban disease (1), transmitted by infected Aedes mosquitoes. Its incidence is increasing in tropical and subtropical areas (1,2) because of 1) introduction of the virus into areas where it was not previously endemic, and 2) the spread of the 4 serotypes and the vector in disease-endemic areas ...
María Jesús Pinazo Delgado +8 more
openaire +2 more sources
Network pharmacology and molecular docking identify bioactive compounds from Eucalyptus globulus essential oil with potential activity against dengue virus, highlighting 70 shared targets and DENV‐2‐associated pathways. Globulol and eucalyptol show strong binding to DENV‐2 receptors, with favorable drug‐likeness and toxicity profiles, supporting their ...
Arslan Afzal +8 more
wiley +1 more source
Background Dengue fever is a hemorrhagic fever caused by flaviviruses. Hemorrhagic manifestations are well known to be associated with dengue fever, though the thrombotic events are only seldom reported. Underlying pathophysiology of thrombotic events is
K. M. I. U. Ranasinghe +3 more
doaj +1 more source
ABSTRACT Dengue remains a major public health concern in Mexico, with incidence and clinical burden increasing substantially in recent years. Using national surveillance data from 2020 to 2024, this study provides a comprehensive overview of the changing epidemiological landscape, with an emphasis on geographic distribution, temporal trends, serotype ...
Blanca Taboada +3 more
wiley +1 more source

