Results 11 to 20 of about 754,759 (237)
Recent Developments in Recombinant Protein–Based Dengue Vaccines [PDF]
Frontiers in Immunology, 2018 Recombinant proteins are gaining enormous importance these days due to their wide application as biopharmaceutical products and proven safety record. Various recombinant proteins of therapeutic and prophylactic importance have been successfully produced ...
Nagesh K. Tripathi, Ambuj Shrivastava
doaj +4 more sources
Dengue Vaccines: An Update. [PDF]
BioDrugs, 2022 Dengue is one of the most prevalent mosquito-borne diseases in the world, affecting an estimated 390 million people each year, according to models. For the last two decades, efforts to develop safe and effective vaccines to prevent dengue virus (DENV) infections have faced several challenges, mostly related to the complexity of conducting long-term ...
Torres-Flores JM +2 more
europepmc +4 more sources
Vaccines licensed and in clinical trials for the prevention of dengue
Human Vaccines and Immunotherapeutics, 2017 Dengue has become a major global public health threat with almost half of the world's population living in at-risk areas. Vaccination would likely represent an effective strategy for the management of dengue disease in endemic regions, however to date ...
J. Torresi, G. Ebert, M. Pellegrini
exaly +4 more sources
A Multi-country Study of the Household Willingness-to-Pay for Dengue Vaccines: Household Surveys in Vietnam, Thailand, and Colombia [PDF]
PLoS Neglected Tropical Diseases, 2015 BACKGROUND:The rise in dengue fever cases and the absence of dengue vaccines will likely cause governments to consider various types of effective means for controlling the disease.
Vittal Mogasale +2 more
exaly +3 more sources
A systematic review on malaria and dengue vaccines for the effective management of these mosquito borne diseases: Improving public health [PDF]
Human Vaccines & ImmunotherapeuticsInsect vector-borne diseases (VBDs) pose significant global health challenges, particularly in tropical and subtropical regions. The WHO has launched the “Global Vector Control Response (GVCR) 2017–2030” to address these diseases, emphasizing a ...
Hind M. Al-Osaimi +12 more
doaj +3 more sources
Dengue vaccines: the road to failure or to success? [PDF]
Human Vaccines & Immunotherapeutics, 2020 A licensed vaccine against dengue was shown to enhance disease under some circumstances, even though it protected most vaccinees. We discuss the implication of these results for the future of dengue vaccines.
Stanley A. Plotkin
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Development of dengue DNA vaccines
Vaccine, 2011 Vaccination with plasmid DNA against infectious pathogens including dengue is an active area of investigation. By design, DNA vaccines are able to elicit both antibody responses and cellular immune responses capable of mediating long-term protection. Great technical improvements have been made in dengue DNA vaccine constructs and trials are underway to
Kevin R Porter
exaly +6 more sources
Detection of post-vaccination enhanced dengue virus infection in macaques: An improved model for early assessment of dengue vaccines. [PDF]
PLoS Pathogens, 2019 The need for improved dengue vaccines remains since the only licensed vaccine, Dengvaxia, shows variable efficacy depending on the infecting dengue virus (DENV) type, and increases the risk of hospitalization for severe dengue in children not exposed to ...
Maria Beatriz Borges +17 more
doaj +3 more sources
Development of Peptide Vaccines in Dengue [PDF]
Current Pharmaceutical Design, 2018 Dengue is one of the most important arboviral infections worldwide, infecting up to 390 million people and causing 25,000 deaths annually. Although a licensed dengue vaccine is available, it is not efficacious against dengue serotypes that infect people living in South East Asia, where dengue is an endemic disease.
Kavita Reginald +2 more
exaly +4 more sources
Dengue Vaccination: A Practical Guide for Clinicians
VaccinesDengue is a growing global public health challenge, with rising incidence and case fatality rates fueled by urbanization and climate change. The substantial mortality, morbidity, and economic burden associated with the disease underscore the need for ...
Kay Choong See
doaj +3 more sources