Impact on health caused by water resources development and management projects and health impact assessment as a tool for mitigation [PDF]
, 2007 Since the rise of early civilisations people have adapted and modified water bodies for their use. Water is made available through dams, wells, canals and other infrastructure to provide drinking water for households and livestock and to feed irrigated
Erlanger, Tobias Ephraim
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Bioethics of establishing a CHIM model for dengue vaccine development
International Journal of Infectious Diseases, 2019 Introduction: Controlled human infection models (CHIM) have been used in vaccine development to up-select and down-select potential vaccine candidates and to provide proof of vaccine efficacy, and have also been used as a basis for licensure of vaccines ...
Anuradha Rose, Amrita Sekhar
doaj +1 more source
Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]
, 2011 BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G. +62 more
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Cytokine patterns during dengue shock syndrome [PDF]
, 2003 Objective. To investigate the patterns of tumor necrosis factor-a (TNF-a), interleukin-1b (IL-1b), IL-6, interferon-c (IFN-c) and interleukin-1 receptor antagonist (IL-1Ra) during the course of dengue shock syndrome. Design. Prospective clinical study.
Suharti, C. +14 more
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Outlook for a dengue vaccine [PDF]
Clinical Microbiology and Infection, 2014 Dengue is an increasing medical problem in subtropical and tropical countries. The search for a safe and effective vaccine is complicated by the fact that there are four types of dengue virus and that, if a vaccine is live attenuated, it should be proven not to cause the life-threatening form of dengue, dengue haemorrhagic fever.
openaire +2 more sources
Risk Factors for Mortality in Dengue Shock Syndrome (DSS) [PDF]
, 2009 Background: Dengue shock syndrome (DSS) is the most severe form of dengue hemorrhagic fever (DHF) and has a high mortality. There are two major pathological changes in DHF determining the severity of disease, plasma leakage and bleeding.
Djokomoeljanto, Robert J +6 more
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Dengue-1 envelope protein domain III along with PELC and CpG oligodeoxynucleotides synergistically enhances immune responses. [PDF]
PLoS Neglected Tropical Diseases, 2012 The major weaknesses of subunit vaccines are their low immunogenicity and poor efficacy. Adjuvants can help to overcome some of these inherent defects with subunit vaccines.
Chen-Yi Chiang +11 more
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Diarrhea and dengue control in rural primary schools in Colombia: study protocol for a randomized controlled trial. [PDF]
, 2012 BACKGROUND: Diarrheal diseases and dengue fever are major global health problems. Where provision of clean water is inadequate, water storage is crucial.
Vargas Sandra +36 more
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Economic impact of dengue illness and the cost-effectiveness of future vaccination programs in Singapore. [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Dengue illness causes 50-100 million infections worldwide and threatens 2.5 billion people in the tropical and subtropical regions. Little is known about the disease burden and economic impact of dengue in higher resourced countries or the ...
Luis R Carrasco +10 more
doaj +1 more source
Age and clinical dengue illness. [PDF]
, 2007 The relationship between age and risk for classic dengue fever has never been quantified. We use data from clinical patients to show that the relative risk of having classical disease after primary dengue virus infection increases with age.
Coleman, Paul G +4 more
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