Results 61 to 70 of about 297,519 (217)
Towards understanding of the replication and pathogenesis of dengue infection [PDF]
, 2007 Dengue is the most important human viral disease transmitted by arthropod vectors and over half of the world's population live in areas at risk of infection. Currently there is neither specific treatment nor vaccine to tackle this emerging disease. The
Umareddy, Indira
core +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Dengue Vaccination: A Practical Guide for Clinicians
VaccinesDengue is a growing global public health challenge, with rising incidence and case fatality rates fueled by urbanization and climate change. The substantial mortality, morbidity, and economic burden associated with the disease underscore the need for ...
Kay Choong See
doaj +1 more source
Deeper understanding about the genetic structure of dengue virus using SVM
MATEC Web of Conferences, 2016 Dengue fever, mainly found in the tropical and subtropical regions, is carried by mosquitoes. With the help of greenhouse effect, places considered to be a Dengue safe-zone are becoming more and more dangerous. Dengue fever shows similar aspects to MERS,
Choi Subin, Choi Hyunjin, Yoon Taeseon
doaj +1 more source
Acta Paediatrica, EarlyView.ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley +1 more source
Frayed Rope and Resilient Threads: Fijian Healthcare and the COVID‐19 Pandemic
Asia Pacific Viewpoint, EarlyView.ABSTRACT In April 2021, Fiji faced international scrutiny due to ‘horrific’ hospital conditions, including staff and patients lacking food, non‐operational operating theatres, and critical shortages of beds, medicine, and equipment. After successfully avoiding a major outbreak in 2020, a sudden surge in COVID‐19 cases in 2021 overwhelmed the public ...
Sharon McLennan +3 more
wiley +1 more source
A tetravalent dengue nanoparticle stimulates antibody production in mice
Journal of Nanobiotechnology, 2012 Background Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However,
Silva Elisângela F +11 more
doaj +1 more source
The Complexity of a Dengue Vaccine: A Review of the Human Antibody Response. [PDF]
PLoS Neglected Tropical Diseases, 2015 Dengue is the most prevalent mosquito-borne viral disease worldwide. Yet, there are no vaccines or specific antivirals available to prevent or treat the disease. Several dengue vaccines are currently in clinical or preclinical stages.
Jacky Flipse, Jolanda M Smit
doaj +1 more source
Health Research Funders and Justice: Obligations to Coordinate and Counterbalance
Bioethics, EarlyView.ABSTRACT Government health research funders are frequently criticized on the grounds that their distribution of resources fails to reflect a population's disease burden. These critiques do not take into account what other research funders are doing. In this paper, I argue that this is a mistake.
Joseph Millum
wiley +1 more source