Results 81 to 90 of about 754,759 (237)
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression
, 2005 Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M +9 more
core +1 more source
Pest Management Science, EarlyView.The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares +8 more
wiley +1 more source
Dengue vaccine: a key for prevention
Expert Review of Vaccines, 2020 Dengue infection is the most important mosquito-borne viral disease in the world. Most mosquito control methods currently available for public health use are not very efficacious. Dengue vaccine is required to control dengue diseases in the future through the use of a safe and effective vaccine.This review covered dengue vaccine development and ...
Usa, Thisyakorn, Terapong, Tantawichien
openaire +2 more sources
Cytokine patterns during dengue shock syndrome [PDF]
, 2003 Objective. To investigate the patterns of tumor necrosis factor-a (TNF-a), interleukin-1b (IL-1b), IL-6, interferon-c (IFN-c) and interleukin-1 receptor antagonist (IL-1Ra) during the course of dengue shock syndrome. Design. Prospective clinical study.
Suharti, C. +14 more
core
Challenges to the Design of Clinical Trials for Live-Attenuated Tetravalent Dengue Vaccines
PLoS Neglected Tropical Diseases, 2016 Viral vaccines do not always produce beneficial results. In the 1960s, formalin-inactivated measles and respiratory syncytial viral vaccines established immune responses in recipient children that rendered them susceptible to severe and fatal disease ...
P. Russell, S. Halstead
semanticscholar +1 more source
Deeper understanding about the genetic structure of dengue virus using SVM
MATEC Web of Conferences, 2016 Dengue fever, mainly found in the tropical and subtropical regions, is carried by mosquitoes. With the help of greenhouse effect, places considered to be a Dengue safe-zone are becoming more and more dangerous. Dengue fever shows similar aspects to MERS,
Choi Subin, Choi Hyunjin, Yoon Taeseon
doaj +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Risk Factors for Mortality in Dengue Shock Syndrome (DSS) [PDF]
, 2009 Background: Dengue shock syndrome (DSS) is the most severe form of dengue hemorrhagic fever (DHF) and has a high mortality. There are two major pathological changes in DHF determining the severity of disease, plasma leakage and bleeding.
Djokomoeljanto, Robert J +6 more
core
A tetravalent dengue nanoparticle stimulates antibody production in mice
Journal of Nanobiotechnology, 2012 Background Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However,
Silva Elisângela F +11 more
doaj +1 more source