Results 81 to 90 of about 297,519 (217)
Is diabetes a risk factor for a severe clinical presentation of dengue? Review and meta-analysis [PDF]
BACKGROUND: The mean age of acute dengue has undergone a shift towards older ages. This fact points towards the relevance of assessing the influence of age-related comorbidities, such as diabetes, on the clinical presentation of dengue episodes ...
Valérie D'Acremont +19 more
core +1 more source
Graphical Abstract and Lay Summary To further increase protein expression, it is imperative to improve cellular performance, a process intrinsically linked to cell metabolism. Hence, a metabolic footprint of Drosophila S2 cells, both recombinant‐ and wild‐types, was performed to enhance the production of the recombinant rabies virus glycoprotein ...
Monize Caiado Decarli +6 more
wiley +1 more source
Efficacy of Multivalent Dengue Vaccine Candidates Predicted In Silico
Background: Dengue virus (DENV) is becoming a global public health problem, but the immunogenicity of DENV structural proteins is not fully understood. Methods: We predicted the epitope-based immunogenicity of DENV proteins from four serotypes in silico ...
Seokhwan Hyeon +6 more
doaj +1 more source
Knowledge, attitude, and practice regarding dengue vaccine: a baseline study of community members and health providers in Indonesia [PDF]
Background Despite recent behavioral interventions aimed at reducing the burden of dengue, persistent unfavorable related behaviors in the Indonesian community suggest that vaccination could be effective.
Abdul Wahab +5 more
doaj +1 more source
Dengue is a public health problem in the tropics and subtropics. There are several vaccine candidates in clinical development. However, there may be gaps in the new vaccine introduction after vaccine licensure before it becomes available in developing countries.
Jacqueline Kyungah, Lim +5 more
openaire +2 more sources
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Corticosteroids for dengue - why don't they work? [PDF]
BACKGROUND: Dysregulated immune responses may contribute to the clinical complications that occur in some patients with dengue. FINDINGS: In Vietnamese pediatric dengue cases randomized to early prednisolone therapy, 81 gene-transcripts (0.2% of the 47 ...
Tuan Trung Vu +61 more
core +2 more sources
Dengue fever is a major public health issue in India because its incidence and mortality rates vary with environmental, social, and infrastructural factors.
Kaliyamoorthy Dass, Rengarajan Murugesan
doaj +1 more source
ABSTRACT Background Dengue is a major mosquito‐borne viral disease worldwide, imposing significant healthcare burden on governments in countries where it is endemic, such as Mexico. This systematic review focused on studies reporting the cost of dengue in Mexico during 2010–2020.
Gilberto Sánchez‐González +2 more
wiley +1 more source

