Results 91 to 100 of about 85,935 (232)

Zoonotic anxieties: The cultural politics of Nepal's quest for pandemic preparedness

Medical Anthropology Quarterly, EarlyView.
Abstract Based on fieldwork conducted in Nepal (2022–2024) and by paying attention to how local and transnational notions of epidemiological risk are deployed, this ethnography introduces the concept of “zoonotic anxieties” to make sense of the multi‐species relational ethos that contemporary global health regimes propose.
Max D. López Toledano, Hari Basnet, Anna Durrance‐Bagale, Natasha Howard   +3 more
wiley   +1 more source

Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR

Indonesian Journal of Biotechnology, 2015
world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detectingdengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primersthat conserve for several Flavivirus.
Nastiti Wijayanti, Tri Wibawa, Hera Nirwati, Aris Haryanto, Sutaryo1 S   +4 more
doaj  

Enhancing Dengue Virus Production and Immunogenicity with Celcradle™ Bioreactor: A Comparative Study with Traditional Cell Culture Methods

Vaccines
The dengue virus, the primary cause of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, is the most widespread mosquito-borne virus worldwide.
Hongxia Guo, Xiaoyan Ding, Dong Hua, Minchi Liu, Maocheng Yang, Yuanxin Gong, Nan Ye, Xiaozhong Chen, Jiuxiang He, Yu Zhang, Xiaofeng Xu, Jintao Li   +11 more
doaj   +1 more source

Panduratin A Induces Autophagy Through AMPK Activation Independent of mTOR Inhibition and Restricts Mycobacterium tuberculosis in Host Macrophages

Molecular Microbiology, EarlyView.
Panduratin A, a flavonoid from Boesenbergia rotunda, was identified as a potential autophagy inducer in macrophages, where it appeared to activate AMPK independently of mTOR. This activity enhanced colocalization of Mycobacterium tuberculosis with autophagosomes and lysosomes, leading to reduced intracellular bacterial survival.
Thomanai Lamtha, Olabisi Flora Davies‐Bolorunduro, Sureeporn Phlaetita, Chernkhwan Kaofai, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Napason Chabang, Bamroong Munyoo, Patoomratana Tuchinda, Suparerk Borwornpinyo, Supawan Jamnongsong, Somponnat Sampattavanich, Prasit Palittapongarnpim, Marisa Ponpuak   +13 more
wiley   +1 more source

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Attenuation and immunogenicity of recombinant yellow fever 17D-dengue type 2 virus for rhesus monkeys

Brazilian Journal of Medical and Biological Research, 2005
A chimeric yellow fever (YF)-dengue serotype 2 (dengue 2) virus was constructed by replacing the premembrane and envelope genes of the YF 17D virus with those from dengue 2 virus strains of Southeast Asian genotype.
Galler R., Marchevsky R.S., Caride E., Almeida L.F.C., Yamamura A.M.Y., Jabor A.V., Motta M.C.A., Bonaldo M.C., Coutinho E.S.F., Freire M.S.   +9 more
doaj  

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

Epidemiological survey and screening strategy for dengue virus in blood donors from Yunnan Province [PDF]

, 2021
Ling Li, Ying Li, Shao-Fang Lu, Jing Dong, Haixia Xu, Qian Zhang, Rong Weng, Yundi Yin, Rui He, Fang Peng, Hua Shi, Yinghan Yu, Ji Wu, Zhong Liu, John R. Hess   +14 more
openalex   +1 more source

Nicotiana benthamiana as a Source of Cowpea Mosaic Virus‐Derived Particles That Specifically Package Designer RNAs

Plant Biotechnology Journal, EarlyView.
ABSTRACT The coupling of replication and encapsidation in the bipartite plant virus, cowpea mosaic virus (CPMV), has been used to specifically incorporate designer RNA molecules into viral particles via transient expression in Nicotiana benthamiana. This is achieved by placing the desired RNA sequence between the 5′ and 3′ UTRs of CPMV RNA‐2 so that ...
H. Peyret, S. N. Shah, Y. Meshcheriakova, J.‐W. Jung, K. Saunders, G. P. Lomonossoff   +5 more
wiley   +1 more source

Ultrastructural Characterization and Three-Dimensional Architecture of Replication Sites in Dengue Virus-Infected Mosquito Cells

, 2014
Jiraphan Junjhon, Janice Pennington, Thomas J. Edwards, Rushika Perera, Jason Lanman, Richard Kühn   +5 more
openalex   +2 more sources