Results 141 to 150 of about 169,398 (330)

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Potential Way to Develop Dengue Virus Detection in Aedes Larvae as an Alternative for Dengue Active Surveillance: A Literature Review

Tropical Medicine and Infectious Disease
The burden of dengue has emerged as a serious public health issue due to its impact on morbidity, mortality, and economic burden. Existing surveillance systems are inadequate to provide the necessary data for the prompt and efficient control of dengue ...
Yenny Rachmawati, Savira Ekawardhani, Nisa Fauziah, Lia Faridah, Kozo Watanabe   +4 more
doaj   +1 more source

The LGALS9/miR‐491‐5p Axis Regulates CD8+ T Cell Function and Inhibits the Progression of Gastric Cancer

Cancer Science, EarlyView.
In this study, we found that LGALS9 is highly expressed in gastric cancer and may affect the development of gastric cancer by participating in the infiltration of CD8+ T cells. Knockout of LGALS9 can reverse T cell function and relieve immunosuppression, and enhance the killing effect of T cells on gastric cancer cells.
Wanzhong Huang, Wei Zheng, Dagao Zhu, Zhi Sun, Wei Lu, Jun Tao, Chen Liu, Liangliang Li, Yingli Zhou, Honghong Fan, Hong Tao, Wenjuan Li   +11 more
wiley   +1 more source

N-butanol Extract of Glycyrrhizae Radix et Rhizoma Inhibits Dengue Virus through Targeting Envelope Protein [PDF]

, 2023
Lingzhu Shi, Xi Chen, Huihui Cao, Chunyang Tian, Lifang Zou, Jianhai Yu, Zibin Lu, Wei Zhao, Junshan Liu, Linzhong Yu   +9 more
openalex   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, EarlyView.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

The FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson, Maura Hofmann, Stefan Mereiter, Lauren Hartley‐Tassell, Masahiro Onji, Irma Sakic, Tiago Oliveira, David Hoffmann, Maria Novatchkova, Alexander Schleiffer, Josef M. Penninger   +10 more
wiley   +1 more source

The Ecological Factors Associated With the Survival, Establishment, and Movement of Aedes aegypti and Ae. albopictus: A Scoping Review

Journal of Applied Entomology, EarlyView.
ABSTRACT Aedes aegypti and Ae. albopictus are mosquito species of public health significance and collectively responsible for the transmission of several arboviruses. Ongoing climatic changes are anticipated to have impacts on their survival, establishment, and movement.
Keana Shahin, Sydney DeWinter, Olaf Berke, Ilaria Dorigatti, Victoria Ng, Katie M. Clow   +5 more
wiley   +1 more source

Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR

Indonesian Journal of Biotechnology, 2015
world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detectingdengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primersthat conserve for several Flavivirus.
Nastiti Wijayanti, Tri Wibawa, Hera Nirwati, Aris Haryanto, Sutaryo1 S   +4 more
doaj  

Enhancing Dengue Virus Production and Immunogenicity with Celcradle™ Bioreactor: A Comparative Study with Traditional Cell Culture Methods

Vaccines
The dengue virus, the primary cause of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, is the most widespread mosquito-borne virus worldwide.
Hongxia Guo, Xiaoyan Ding, Dong Hua, Minchi Liu, Maocheng Yang, Yuanxin Gong, Nan Ye, Xiaozhong Chen, Jiuxiang He, Yu Zhang, Xiaofeng Xu, Jintao Li   +11 more
doaj   +1 more source

CRISPR‐Enhanced RAA‐SHERLOCK Assay for Point‐of‐Care Detection of Cyprinid Herpesvirus‐3: Development, Validation and Clinical Application

Journal of Fish Diseases, EarlyView.
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Hatem Soliman, Naveed Akram, Mona Saleh
wiley   +1 more source