Results 181 to 190 of about 1,855,785 (322)
New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti+13 more
wiley +1 more source
Nonspecific Factors in Monkey Tissues and Serum Causing Inhibition of Plaque Formation and Hemagglutination by Dengue Viruses [PDF]
Donald R. Nash+3 more
openalex +1 more source
Adaptive immune responses to primary and secondary dengue virus infections
A. S. St. John, Abhay P. S. Rathore
semanticscholar +1 more source
The natural and anthropized wetland of Gándaras de Budiño (Galicia, Spain) hosts a great number of mosquito species. Culex pipiens s.l. and Culex torrentium pose an emerging risk for West Nile virus transmission. The temporary and polluted waters, as well as the summer and spring seasons, favor the larval proliferation of these vectors.
Yasmina Martínez‐Barciela+2 more
wiley +1 more source
The introduction and establishment of dengue disease in a new area: a mini review [PDF]
Dengue fever virus is a mosquito-borne virus that poses a significant public health threat worldwide. Dengue virus is primarily transmitted by the Aedes mosquitoes, which develop in small man-made containers in urban environments.
Hassan Nasirian
doaj
Dengue Virus Plaque Development in Simian Cell Systems [PDF]
Thomas B. Stim
openalex +1 more source
ABSTRACT Emerging and important endemic viral diseases without effective antiviral are important public health threat. An effective broad‐spectrum antiviral can be a pivotal tool to mitigate future epidemics and provide a solution for endemic viral diseases. Molnupiravir, a pyrimidine analog, is known for the COVID‐19 treatment.
Thanyaporn Sirihongthong+4 more
wiley +1 more source
Isolation and identification of the etiologic virus of dengue
Susumu Hotta
openalex +2 more sources
Alveolar macrophages (AMs)—the most numerous immune cells of the lung—respond to viral infections by secreting cytokines to summon other immune cells. We investigated whether AMs recognize SARS‐CoV‐2 proteins and how they respond. AMs did not sense spike protein but did recognize envelope protein via the pattern recognition receptors TLR2 and TLR4 ...
Conor Grant+6 more
wiley +1 more source
ABSTRACT Background In the last three decades, West Nile virus (WNV, Flaviviridae, Orthoflavivirus genus) has become one of the most important encephalitic agents worldwide, causing substantial numbers of cases in humans and horses every year by re‐emerging in endemic areas and emerging in new territories.
Csenge Hanna Tolnai+7 more
wiley +1 more source