Results 181 to 190 of about 1,855,785 (322)

New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity

open access: yesChemMedChem, Volume 20, Issue 13, July 1, 2025.
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti   +13 more
wiley   +1 more source

Adaptive immune responses to primary and secondary dengue virus infections

open access: yesNature reviews. Immunology, 2019
A. S. St. John, Abhay P. S. Rathore
semanticscholar   +1 more source

Abundance, Diversity and Phenology of Mosquito Larvae in a Highly Anthropized Wetland: Health and Management Implications of Gándaras de Budiño (NW Spain)

open access: yesEcology and Evolution, Volume 15, Issue 7, July 2025.
The natural and anthropized wetland of Gándaras de Budiño (Galicia, Spain) hosts a great number of mosquito species. Culex pipiens s.l. and Culex torrentium pose an emerging risk for West Nile virus transmission. The temporary and polluted waters, as well as the summer and spring seasons, favor the larval proliferation of these vectors.
Yasmina Martínez‐Barciela   +2 more
wiley   +1 more source

The introduction and establishment of dengue disease in a new area: a mini review [PDF]

open access: yesCaspian Journal of Health Research
Dengue fever virus is a mosquito-borne virus that poses a significant public health threat worldwide. Dengue virus is primarily transmitted by the Aedes mosquitoes, which develop in small man-made containers in urban environments.
Hassan Nasirian
doaj  

In Vitro Synergistic Antiviral Effects of β‐D‐N4‐hydroxycytidine and Teriflunomide in Combination against a Broad Range of RNA Viruses

open access: yesJournal of Medical Virology, Volume 97, Issue 7, July 2025.
ABSTRACT Emerging and important endemic viral diseases without effective antiviral are important public health threat. An effective broad‐spectrum antiviral can be a pivotal tool to mitigate future epidemics and provide a solution for endemic viral diseases. Molnupiravir, a pyrimidine analog, is known for the COVID‐19 treatment.
Thanyaporn Sirihongthong   +4 more
wiley   +1 more source

Human Alveolar Macrophages Detect SARS‐CoV‐2 Envelope Protein Through TLR2 and TLR4 and Secrete Cytokines in Response

open access: yesImmunology, Volume 175, Issue 3, Page 391-401, July 2025.
Alveolar macrophages (AMs)—the most numerous immune cells of the lung—respond to viral infections by secreting cytokines to summon other immune cells. We investigated whether AMs recognize SARS‐CoV‐2 proteins and how they respond. AMs did not sense spike protein but did recognize envelope protein via the pattern recognition receptors TLR2 and TLR4 ...
Conor Grant   +6 more
wiley   +1 more source

Long‐Term Humoral Immune Response After West Nile Virus Convalescence in Horses in a Geographic Area of Multiple Orthoflavivirus Co‐Circulation

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background In the last three decades, West Nile virus (WNV, Flaviviridae, Orthoflavivirus genus) has become one of the most important encephalitic agents worldwide, causing substantial numbers of cases in humans and horses every year by re‐emerging in endemic areas and emerging in new territories.
Csenge Hanna Tolnai   +7 more
wiley   +1 more source

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