System Analysis of Dengue Virus Surveillance in BBTKL PP Surabaya Year 2012–2014
Changing the distribution of dengue virus serotypes has occurred in Indonesia. This condition should be monitored continuously through the Dengue Virus Surveillance. Implementation of Dengue Virus Surveillance also conducted by BBTKL PP Surabaya.
Atina Husnayain +2 more
doaj +1 more source
Increased PAI-1 plasma levels and risk of death from dengue: no association with the 4G/5G promoter polymorphism [PDF]
Background: Dengue virus infected patients have high plasminogen activator inhibitor type I (PAI-1) plasma concentrations. Whether the insertion/deletion (4G/5G) polymorphism in the promotor region of the PAI-1 gene is associated with increased PAI-1 ...
ten Cate, H +10 more
core +4 more sources
Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR
world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detecting dengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primers that conserve for several ...
Nastiti Wijayanti +4 more
doaj +1 more source
Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira +30 more
core +2 more sources
Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity
Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Ramil R. Mintaev +6 more
doaj +1 more source
Background: Dengue is a rapidly emerging arthropod borne viral infection affecting tropical and sub-tropical regions of the world. Dengue is an acute febrile illness but sometimes causes more fatal complications like dengue haemorrhagic fever (DHF) and ...
Nazish Parveen +9 more
doaj +1 more source
Polytope Prediction for Dengue Vaccine Candidate Based on Conserved Envelope Glycoprotein of Four Serotypes of Dengue Virus and Its Antigenicity [PDF]
Dengue fever reported endemic in tropical and sub-tropical country. Dengue fever caused by dengue virus, has Envelope protein that often used for vaccine development to prevent the virus infection.
Karimatul Himmah +4 more
doaj +1 more source
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Investigation of denugue virus envelope gene quasispecies variation in patient samples : implications for virus virulence and disease pathognesis [PDF]
Due to the error-prone nature of RNA virus replication, each dengue virus (DV) exists as a quasispecies within the host. To investigate the hypothesis that DV quasispecies populations affect disease severity, serum samples were obtained from dengue ...
Love, Hannah
core +2 more sources
Pathogenic viruses have RNA genomes that cause acute and chronic infections. These viruses replicate with high mutation rates and exhibit significant genetic diversity, so-called viral quasispecies. Viral quasispecies play an important role in chronic infectious diseases, but little is known about their involvement in acute infectious diseases such as ...
openaire +3 more sources

