Results 121 to 130 of about 3,321,801 (325)

Utility of supplemental screening with breast ultrasound in asymptomatic women with dense breast tissue who are not at high risk for breast cancer

Indian Journal of Radiology and Imaging, 2017
Objective: To assess the results of an initial round of supplemental screening with hand-held bilateral breast ultrasound following a negative screening mammogram in asymptomatic women with dense breast tissue who are not at high risk for breast cancer ...
Geetika A Klevos, Fernando Collado-Mesa, Jose M Net, Monica M Yepes   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Frequency and Phenotype of Coexisting Aquaporin‐4 and Autoimmune Encephalitis Autoantibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Among 9457 aquaporin‐4 (AQP4) immunoglobulin G‐positive patients, 2071 underwent autoimmune encephalitis antibody testing and 85 (4%) had coexisting antibodies, most commonly cerebrospinal fluid glial fibrillary acidic protein‐IgG and N‐methyl‐D‐aspartate receptor‐IgG, or serum high‐titer GAD65‐IgG.
Laura Cacciaguerra, Binxia Yang, Vanda A. Lennon, Shruti P. Agnihotri, Nusrat Ahsan, Karen S. Fernandez, Erin McLeod, Georgios Mangioris, William R. Meador, Wendy G. Mitchell, Jacqueline A. Nicholas, Amy M. L. Quek, Thomas Shoemaker, Kurt Sieloff, Matt C. Edmond, Rebekah A. Laggis, Kristin L. Flynn, Jessica A. Sagen, Emmanuelle Waubant, John J. Chen, Sarosh R. Irani, Andrew McKeon, Anastasia Zekeridou, Eoin P. Flanagan, Sean J. Pittock, Amy Kunchok   +25 more
wiley   +1 more source

Dense breast tissue in postmenopausal women is associated with a pro-inflammatory microenvironment in vivo

Oncoimmunology, 2016
Inflammation is one of the hallmarks of carcinogenesis. High mammographic density has been associated with increased risk of breast cancer but the mechanisms behind are poorly understood. We evaluated whether breasts with different mammographic densities
Annelie Abrahamsson, Anna Rzepecka, Thobias Romu, M. Borga, O. Leinhard, P. Lundberg, J. Kihlberg, C. Dabrosin   +7 more
semanticscholar   +1 more source

Association of conventional risk factors, BMI, mean breast dense area and GRS with breast cancer.

, 2015
Note: vGail—Variables from the Gail modelAssociation of conventional risk factors, BMI, mean breast dense area and GRS with breast cancer.
Mikael Hartman (77255), Wen Yee Chay (799692), Khee Chee Soo (258918), Min-Han Tan (270806), Charmaine Pei Ling Lee (799689), Hyungwon Choi (86478), Jingmei Li (254314), Kee Seng Chia (28193), Jenny Liu (647696)   +8 more
core   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Digital breast tomosynthesis and automated breast ultrasound: added values in women with dense breasts

The Egyptian Journal of Radiology and Nuclear Medicine
Background Dense breast is one of the challenging cases in breast imaging; in both screening and diagnostic settings. Digital mammography (DM) is the first line modality for breast imaging.
Rabab Hassan Gouda, Maha Helal, Azza Mohamed Nasr, Ahmed Mohamed Farahat, S W Y Gareer, Hebatalla Hassan el kassas, Abeer Ali El-Sharawy   +6 more
doaj   +1 more source

Breast Cancer Detection using Sonography in Women with Mammographically Dense Breast [PDF]

, 2017
BACKGROUND: Mammography is the gold standard imaging modality for screening and diagnosis of breast cancer with advances in treatment. Ultrasonography is the supplemental tool in evaluating the dense breast.
Gomathi, G
core