Results 91 to 100 of about 217,760 (286)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Occlusion Detection of Dense Correspondence Fields Using Motion Statistics and Triangulation

open access: yesIEEE Access, 2019
Despite progress made in the accuracy and robustness of the dense matching technique in past years, efficient occlusion detection remains an open problem.
Chong Dong   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

DCTM: Discrete-Continuous Transformation Matching for Semantic Flow

open access: yes, 2017
Techniques for dense semantic correspondence have provided limited ability to deal with the geometric variations that commonly exist between semantically similar images.
Kim, Seungryong   +3 more
core   +1 more source

Geometric Image Correspondence Verification by Dense Pixel Matching

open access: yes, 2019
This paper addresses the problem of determining dense pixel correspondences between two images and its application to geometric correspondence verification in image retrieval. The main contribution is a geometric correspondence verification approach for re-ranking a shortlist of retrieved database images based on their dense pair-wise matching with the
Laskar, Zakaria   +4 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Object-Oriented Hierarchy Radiation Consistency for Different Temporal and Different Sensor Images

open access: yesSensors, 2018
In the paper, we propose a novel object-oriented hierarchy radiation consistency method for dense matching of different temporal and different sensor data in the 3D reconstruction.
Nan Su   +3 more
doaj   +1 more source

SceneFlowFields: Dense Interpolation of Sparse Scene Flow Correspondences

open access: yes, 2017
While most scene flow methods use either variational optimization or a strong rigid motion assumption, we show for the first time that scene flow can also be estimated by dense interpolation of sparse matches.
Bailer, Christian   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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