Results 81 to 90 of about 216,940 (284)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

AN AUTOMATIC FILTER ALGORITHM FOR DENSE IMAGE MATCHING POINT CLOUDS [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017
Although many filter algorithms have been presented over past decades, these algorithms are usually designed for the Lidar point clouds and can’t separate the ground points from the DIM (dense image matching, DIM) point clouds derived from the oblique ...
Y. Q. Dong, Y. Q. Dong, L. Zhang, X. M. Cui, H. B. Ai   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Building Change Detection from Historical Aerial Photographs Using Dense Image Matching and Object-Based Image Analysis

Remote Sensing, 2014
A successful application of dense image matching algorithms to historical aerial photographs would offer a great potential for detailed reconstructions of historical landscapes in three dimensions, allowing for the efficient monitoring of various ...
Stephan Nebiker, Natalie Lack, Marianne Deuber   +2 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

STEREO IMAGE DENSE MATCHING BY INTEGRATING SIFT AND SGM ALGORITHM [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Semi-global matching(SGM) performs the dynamic programming by treating the different path directions equally. It does not consider the impact of different path directions on cost aggregation, and with the expansion of the disparity search range, the ...
Y. Zhou, Y. Song, J. Lu
doaj   +1 more source

PWC-Net: CNNs for Optical Flow Using Pyramid, Warping, and Cost Volume

, 2018
We present a compact but effective CNN model for optical flow, called PWC-Net. PWC-Net has been designed according to simple and well-established principles: pyramidal processing, warping, and the use of a cost volume. Cast in a learnable feature pyramid,
Kautz, Jan, Liu, Ming-Yu, Sun, Deqing, Yang, Xiaodong   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

On the Design and Analysis of Multiple View Descriptors [PDF]

, 2013
We propose an extension of popular descriptors based on gradient orientation histograms (HOG, computed in a single image) to multiple views. It hinges on interpreting HOG as a conditional density in the space of sampled images, where the effects of ...
Balzer, Jonathan, Davis, Damek, Dong, Jingming, Hernandez, Joshua, Soatto, Stefano   +4 more
core  

Dense image matching for close range photogrammetry

, 2016
Dichte Bildzuordnung ermöglicht die Berechnung von 3D Oberflächen aus mindestens zwei Bildern durch die Lösung des Korrespondenzproblems für jedes Pixel. Anhand der Korrespondenzinformation und der bekannten Kamerageometrie kann die Tiefeninformation durch einen Schnitt der Sichtstrahlen im Raum rekonstruiert werden.
openaire   +3 more sources