Results 91 to 100 of about 904,708 (330)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A laboratory method for precisely determining the micro-volume-magnitudes of liquid efflux [PDF]

open access: yes, 1969
Micro-volumetric quantities of ejected liquid are made to produce equal volumetric displacements of a more dense material. Weight measurements are obtained on the displaced heavier liquid and used to calculate volumes based upon the known density of the ...
Cloutier, R. L.
core   +1 more source

The dense warm ionized medium in the inner Galaxy [PDF]

open access: bronze, 2021
W. D. Langer   +8 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Physical Cleaning of Lakhra Coal by Dense Medium Separation Method [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2015
This research is an attempt to upgrade Lakhra Lignite Coal using ?Dense Medium Separation? technique, to make it techno-environmentally acceptable product for different industries.
Sikandar Ali Channa   +2 more
doaj  

Extending Soft-Collinear-Effective-Theory to describe hard jets in dense QCD media

open access: yes, 2009
An extension to the Soft-Collinear-Effective Theory (SCET) description of hard jets is motivated to include the leading contributions between the propagating partons within the jet with partons radiated from a dense extended medium.
Abhijit Majumder   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Jet Quenching and Correlations

open access: yes, 2014
This article reviews recent advances in our understanding of the experimental aspects of jet-quenching and correlations in relativistic heavy-ion collisions at RHIC and LHC.
Wang, Fuqiang
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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