Results 111 to 120 of about 330,584 (291)

High gas-pressure apparatus for nonlinear X-ray propagation and reshaping via stimulated X-ray Raman scattering

Scientific Reports
We describe an experimental setup for non-linear interaction and propagation of ultrashort and intense x-ray free-electron laser (XFEL) pulses in a dense gas.
Alexander Magunia, Marc Rebholz, Tommaso Mazza, Alberto De Fanis, Thomas M. Baumann, Sergey Usenko, Nils Rennhack, Kai Li, Marc Simon, Marcus Agåker, Jan-Erik Rubensson, Michael Meyer, Linda Young, Christian Ott, Thomas Pfeifer   +14 more
doaj   +1 more source

Research on Intraparticle to Interparticle Entanglement Swapping Protocols

Applied Sciences
Entanglement is one of the most striking features of quantum systems, whereby its non-classical correlation is an essential resource in numerous quantum protocols.
Jiangmei Tang, Shaomeng Wang, Bingyang Liang, Yubin Gong   +3 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Digging into the Interior of Hot Cores with ALMA (DIHCA). VI. The Formation of Low-mass Multiple Systems in High-mass Cluster-forming Regions

The Astrophysical Journal
Most stars form in multiple systems, with profound implications in numerous astronomical phenomena intrinsically linked to multiplicity. However, our knowledge about the process of how multiple stellar systems form is incomplete and biased toward nearby ...
Qiu-yi Luo, Patricio Sanhueza, Stella S. R. Offner, Fernando Olguin, Adam Ginsburg, Fumitaka Nakamura, Kaho Morii, Yu Cheng, Kei E. I. Tanaka, Junhao Liu, Tie Liu, Xing Lu, Qizhou Zhang, Kotomi Taniguchi, Piyali Saha, Shanghuo Li, Xiaofeng Mai   +16 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Effects of Oil Properties on Stability Behavior of High-Energy-Density Fat Emulsions

Foods
Foods for special medical purposes play a critical role in clinical nutritional support, especially oil-in-water emulsions characterized as having high energy density, which could provide efficient energy for patients with insufficient intake or those ...
Xianmin Xu, Wei Zeng, Meijun Du, Abdelaziz Elbarbary, Jun Jin, Xingguo Wang   +5 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A Bottom-Up Multi-Feature Fusion Algorithm for Individual Tree Segmentation in Dense Rubber Tree Plantations Using Unmanned Aerial Vehicle–Light Detecting and Ranging

Plants
Accurate individual tree segmentation (ITS) in dense rubber plantations is a challenging task due to overlapping canopies, indistinct tree apexes, and intricate branch structures.
Zhipeng Zeng, Junpeng Miao, Xiao Huang, Peng Chen, Ping Zhou, Junxiang Tan, Xiangjun Wang   +6 more
doaj   +1 more source