Results 91 to 100 of about 3,437,879 (280)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

CFD based study of dense medium drum separation processes

, 2017
Dense Medium Drum (DMD) separation is applied particularly in the coal and recycling industries. Characteristic of the process is a separation based on density, driven by the buoyancy and gravitational forces acting on an object moving in a free surface ...
Vanierschot, Maarten, Eggers, Arne, Baelmans, Martine   +2 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Label-free separation of peripheral blood mononuclear cells from whole blood by gradient acoustic focusing

Scientific Reports
Efficient techniques for separating target cells from undiluted blood are necessary for various diagnostic and research applications. This paper presents acoustic focusing in dense media containing iodixanol to purify peripheral blood mononuclear cells ...
Julia Alsved, Mahdi Rezayati Charan, Pelle Ohlsson, Anke Urbansky, Per Augustsson   +4 more
doaj   +1 more source

Research progress and outlook of efficient dry separation of fine coal

Meitan xuebao
As the primary energy source in China, coal plays a crucial role in national energy security. More than two-thirds of coal reserves are distributed in arid and water-scarce regions. Low-quality coal accounts for approximately 40% of total resources. With
Chenlong DUAN, Yangfan XU, Bo ZHANG, Liang DONG, Enhui ZHOU, Weinan WANG, Miao PAN, Chenyang ZHOU   +7 more
doaj   +1 more source

Continuous float-sink density separation of lump iron ore using a dry sand fluidized bed dense medium

, 2013
C1 - Journal Articles RefereedA continuous separator based on float–sink density separation using a gas–solid fluidized bed dense medium was used to upgrade iron ore.
Yoshida, M, Kajimoto, S, Oshitani, J, Franks, GV, Kubo, Y, Nakatsukasa, S   +5 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Mineralogical effects on the dense medium separation of low grade nickel sulfide ore [PDF]

, 2015
Dense medium separation (DMS) is a method often used to upgrade base metal sulfide (BMS) ores before their main processing stage, with varying results achieved for different ore types.
Pillay, Keshree
core   +1 more source

Application of density tracers in a dense medium circuit: A case study

, 2018
Density tracers are often used to identify the separation efficiency of mineral processing equipment and the overall plant performance in several mineral and coal applications.
ÖZCAN, ÖZGÜR, ORHAN, EREN CANER, İZERDEM, DAMLA, ALPAY, E.   +3 more
core   +1 more source